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The reference range for total protein is typically 60-80g/L. (It is also sometimes reported as "6.0-8.0g/dl"), [2] but this may vary depending on the method of analysis. Concentrations below the reference range usually reflect low albumin concentration, for instance in liver disease or acute infection.
4036 14725 Ensembl ENSG00000081479 ENSMUSG00000027070 UniProt P98164 A2ARV4 RefSeq (mRNA) NM_004525 NM_001081088 RefSeq (protein) NP_004516 NP_001074557 Location (UCSC) Chr 2: 169.13 – 169.36 Mb Chr 2: 69.25 – 69.42 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Low density lipoprotein receptor-related protein 2 also known as LRP-2 or megalin is a protein which in humans is ...
This is typically seen as a broadening of the alpha-2 zone. Alpha-2 macroglobulin may be elevated in children and the elderly. This is seen as a sharp front to the alpha-2 band. AMG is markedly raised (10-fold increase or greater) in association with glomerular protein loss, as in nephrotic syndrome. Due to its large size, AMG cannot pass ...
It was originally coined in reference to the use of limited proteolysis to investigate contact sites within a monoclonal antibody - protein antigen complex [1] and a year later to examine the protection from hydroxyl radical cleavage conferred by a protein bound to DNA within a DNA-protein complex. [2] In DNA footprinting the protein is ...
The method combines the reactions of copper ions with the peptide bonds under alkaline conditions (the Biuret test) with the oxidation of aromatic protein residues. The Lowry method is based on the reaction of Cu +, produced by the oxidation of peptide bonds, with Folin–Ciocalteu reagent (a mixture of phosphotungstic acid and phosphomolybdic acid in the Folin–Ciocalteu reaction).
Immunoprecipitation of intact protein complexes (i.e. antigen along with any proteins or ligands that are bound to it) is known as co-immunoprecipitation (Co-IP). Co-IP works by selecting an antibody that targets a known protein that is believed to be a member of a larger complex of proteins.
One drop of CSF sample (collected from the patient by lumbar puncture technique), is added to about 1ml of Pandy's solution. The turbid appearance signifies the presence of elevated levels of globulin protein in the CSF and is regarded as positive Pandy's reaction.
Toll-like receptor 2 also known as TLR2 is a protein that in humans is encoded by the TLR2 gene. [5] TLR2 has also been designated as CD282 ( cluster of differentiation 282). TLR2 is one of the toll-like receptors and plays a role in the immune system .