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Iopamidol , sold under the brand name Isovue among others, is a nonionic, low-osmolar iodinated contrast agent, developed by Bracco Diagnostics. It is available in various concentrations, from 200 to 370 mgI/mL.
Contrast CT of a patient with brain metastases from breast cancer, before (left) and after (right) injection of iodinated contrast.. Iodinated contrast is a form of water-soluble, intravenous radiocontrast agent containing iodine, which enhances the visibility of vascular structures and organs during radiographic procedures.
Iodinated contrast contains iodine.It is the main type of radiocontrast used for intravenous administration.Iodine has a particular advantage as a contrast agent for radiography because its innermost electron ("k-shell") binding energy is 33.2 keV, similar to the average energy of x-rays used in diagnostic radiography.
V08AB Water-soluble, nephrotropic, low osmolar X-ray contrast media. V08AB01 Metrizamide V08AB02 Iohexol V08AB03 Ioxaglic acid V08AB04 Iopamidol V08AB05 Iopromide
The osmolality of iohexol ranges from 322 mOsm/kg—approximately 1.1 times that of blood plasma—to 844 mOsm/kg, almost three times that of blood. [11] Despite this difference, iohexol is still considered a low-osmolality contrast agent; the osmolality of older agents, such as diatrizoate, may be more than twice as high.
Iopromide is an iodinated contrast medium for X-ray imaging.It is marketed under the name Ultravist which is produced by Bayer Healthcare. It is a low osmolar, non-ionic contrast agent for intravascular use; i.e., it is injected into blood vessels.
Diatrizoate, also known as amidotrizoate, Gastrografin, is a contrast agent used during X-ray imaging. [1] This includes visualizing veins, the urinary system, spleen, and joints, as well as computer tomography (CT scan). [1] It is given by mouth, injection into a vein, injection into the bladder, through a nasogastric tube, or rectally. [2] [3]
When used as tissue contrast, iodized oil has a risk of entering the vein and causing embolism in the brain and lungs. [5] There is a boxed warning referring to the risk of embolism. [ 6 ] Use as iodine supplementation is recommended in regions where deficiency is common, otherwise it is not recommended. [ 4 ]