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N,N-Dimethyltryptamine (DMT or N,N-DMT) is a substituted tryptamine that occurs in many plants and animals, including humans, and which is both a derivative and a structural analog of tryptamine. [ 1 ] [ 2 ] [ 3 ] DMT is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen .
Tryptamine is an indolamine metabolite of the essential amino acid tryptophan. [9] [10] The chemical structure is defined by an indole—a fused benzene and pyrrole ring, and a 2-aminoethyl group at the second carbon (third aromatic atom, with the first one being the heterocyclic nitrogen). [9]
[1] α,N-DMT is known to be a potent monoamine oxidase inhibitor and tryptamine or serotonin receptor antagonist. [2] [1] Close analogues of α,N-DMT, such as α-methyltryptamine (αMT), are known to act as monoamine releasing agents and serotonin receptor agonists. [3] α,N-DMT is the N-methylated analogue of αMT. [1]
For example, East Asian tea ceremony is a ritualized practice of making and serving tea (茶 cha) in East Asia practiced in the Sinosphere. Tea has been drunk by Buddhist monks since the Sui Dynasty (589–618 BC) to maintain a state of "mindful alertness" during long periods of meditation. Tea ceremonies have been ritualized for centuries.
NMT is an alkaloid derived from L-tryptophan that has been found in the bark, shoots and leaves of several plant genera, including Virola, Acacia, Mimosa, and Desmanthus—often together with the related compounds N,N-dimethyltryptamine (DMT) and 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT). [4]
The Food and Drug Administration announced it was investigating "the possible hallucinogenic effects of banana peels". Nonetheless, bananadine became more widely known when William Powell , believing the Berkeley Barb article to be true, reproduced the method in The Anarchist Cookbook in 1970, under the name " Musa sapientum Bananadine ...
Under American federal law, DMT is a Schedule I drug that is illegal to possess or consume; however, certain religious groups have been legally permitted to consume ayahuasca. [121] A court case allowing the União do Vegetal to import and use the tea for religious purposes in the United States, Gonzales v.
Senegalia chundra, DMT and other tryptamines in leaf, bark [citation needed] Acacia colei, DMT [19] Acacia complanata, 0.3% alkaloids in leaf and stem, almost all N-methyl-tetrahydroharman, with traces of tetrahydroharman, some of tryptamine [20] [21] [22] Acacia confusa, DMT & NMT in leaf, stem & bark 0.04% NMT and 0.02% DMT in stem. [9]
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