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1942 – benzylpenicillin, the first penicillin; 1942 – gramicidin S, the first peptide antibiotic; 1942 – sulfadimidine; 1943 – sulfamerazine; 1944 – streptomycin, the first aminoglycoside [2] 1947 – sulfadiazine; 1948 – chlortetracycline, the first tetracycline; 1949 – chloramphenicol, the first amphenicol [2] 1949 – neomycin
In 1907 Alfred Bertheim synthesized Arsphenamine, the first man-made antibiotic. In 1927 Erik Rotheim patented the first aerosol spray can. In 1933 Robert Pauli Scherer created a method to develop softgels. William Roberts studies about penicillin were continued by Alexander Fleming, who in 1928 concluded that penicillin had an antibiotic ...
Most cases of pneumonia were contracted in hospitals, and many of these were antibiotic-resistant strains that had been nurtured there. [227] In 1965, the first case of penicillin resistance in Streptococcus pneumoniae was reported from Boston. [228] [229] Since then other strains and species of bacteria have developed resistance. [217]
[20] [22] These drugs were later renamed antibiotics by Selman Waksman, an American microbiologist, in 1947. [23] The term antibiotic was first used in 1942 by Selman Waksman and his collaborators in journal articles to describe any substance produced by a microorganism that is antagonistic to the growth of other microorganisms in high dilution.
The history of syphilis has been well studied, but the exact origin of the disease remains unknown. [3] It appears to have originated in both Africa and America. [4] [5] As such, there are two primary hypotheses: one proposes that syphilis was carried to Europe from the Americas by the crew(s) of Christopher Columbus as a byproduct of the Columbian exchange, while the other proposes that ...
Production of antibiotics is a naturally occurring event, that thanks to advances in science can now be replicated and improved upon in laboratory settings. Due to the discovery of penicillin by Alexander Fleming, and the efforts of Florey and Chain in 1938, large-scale, pharmaceutical production of antibiotics has been made possible.
Lloyd Hillyard Conover (June 13, 1923 – March 11, 2017) was an American chemist and the inventor of tetracycline. For this invention, he was inducted into the National Inventors Hall of Fame. [1] Conover was the first to make an antibiotic by chemically modifying a naturally produced drug. [2] He had close to 300 patents to his name.
In December 1942, survivors of the Cocoanut Grove fire in Boston were the first burn patients to be successfully treated with penicillin. [90] The first successful use of pure penicillin was in 1942 when Fleming cured Harry Lambert of an infection of the nervous system (streptococcal meningitis) which would otherwise have been fatal. By that ...