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57,541 copies of the FreeSurfer software package have been registered for use as of April 2022 [5] and it is a core tool in the processing pipelines of the Human Connectome Project, [6] the UK Biobank, [7] the Adolescent Brain Cognitive Development Study, [8] and the Alzheimer's Disease Neuroimaging Initiative.
Human Connectome Project – 2009 NIH $30 million project to build a network map of the human brain, including structural (anatomical) and functional elements. Emphasis included research into dyslexia, autism, Alzheimer's disease, and schizophrenia. See also Connectome a, comprehensive map of neural connections in the brain.
The first MR images of a human brain were obtained in 1978 by two groups of researchers at EMI Laboratories led by Ian Robert Young and Hugh Clow. [1] In 1986, Charles L. Dumoulin and Howard R. Hart at General Electric developed MR angiography, [2] and Denis Le Bihan obtained the first images and later patented diffusion MRI. [3]
The connectogram, as a graphical representation of brain connectomics, was proposed in 2012. [1]Circular representations of connections have been used in a number of disciplines; examples include representation of aspects of epidemics, [2] geographical networks, [3] musical beats, [4] diversity in bird populations, [5] and genomic data. [6]
Connectomics is the production and study of connectomes: comprehensive maps of connections within an organism's nervous system.More generally, it can be thought of as the study of neuronal wiring diagrams with a focus on how structural connectivity, individual synapses, cellular morphology, and cellular ultrastructure contribute to the make up of a network.
A connectome (/ k ə ˈ n ɛ k t oʊ m /) is a comprehensive map of neural connections in the brain, and may be thought of as its "wiring diagram". [2] An organism's nervous system is made up of neurons which communicate through synapses. A connectome is constructed by tracing the neuron in a nervous system and mapping where neurons are ...
Brain mapping is a set of neuroscience techniques predicated on the mapping of (biological) quantities or properties onto spatial representations of the (human or non-human) brain resulting in maps.
The WU-Minn-Oxford consortium developed improved MRI instrumentation, image acquisition and image analysis methods for mapping the connectivity in the human brain at spatial resolutions significantly better than previously available; using these methods, WU-Minn-Oxford consortium collected a large amount of MRI and behavioral data on 1,200 healthy adults — twin pairs and their siblings from ...