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  2. Congenital insensitivity to pain - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    A patient and doctor discuss congenital insensitivity to pain. For people with this disorder, cognition and sensation are otherwise normal; for instance, patients can still feel discriminative touch (though not always temperature [3]), and there are generally no detectable physical abnormalities.

  3. Congenital insensitivity to pain with anhidrosis - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    Since people with this condition are unable to sweat, they are unable to properly regulate their body temperature. [1] Those affected are unable to feel pain and temperature. [2] [3] The absence of pain experienced by people with CIPA puts them at high risk for accidental self-injury. Corneal ulceration occurs due to lack of protective impulses ...

  4. Nociceptor - Wikipedia

    en.wikipedia.org/wiki/Nociceptor

    ' pain receptor ') is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat" signals [1] [2] [3] to the spinal cord and the brain. The brain creates the sensation of pain to direct attention to the body part, so the threat can be mitigated; this process is called nociception.

  5. Pain and pleasure - Wikipedia

    en.wikipedia.org/wiki/Pain_and_pleasure

    Not only have Siri Leknes and Irene Tracey, two neuroscientists who study pain and pleasure, concluded that pain and reward processing involve many of the same regions of the brain, but also that the functional relationship lies in that pain decreases pleasure and rewards increase analgesia, which is the relief from pain.

  6. Gate control theory - Wikipedia

    en.wikipedia.org/wiki/Gate_control_theory

    Afferent pain-receptive nerves, those that bring signals to the brain, comprise at least two kinds of fibers - a fast, relatively thick, myelinated "Aδ" fiber that carries messages quickly with intense pain, and a small, unmyelinated, slow "C" fiber that carries the longer-term throbbing and chronic pain. Large-diameter Aβ fibers are ...

  7. Unsurprisingly, Women Experience Pain Differently Than Men ...

    www.aol.com/unsurprisingly-women-experience-pain...

    One is that the meditation-based pain relief was less effective in men when the opioid system was blocked, which suggested that they tend to rely on the body’s opioid production to reduce pain.

  8. Mechanosensation - Wikipedia

    en.wikipedia.org/wiki/Mechanosensation

    Aδ fibers are characterized by thin axons and thin myelin sheaths, and are either D-hair receptors or nociceptive neurons. Aδ fibers conduct at a rate of up to 25 m/s. D-hair receptors have large receptive fields and very low mechanical thresholds, and have been shown to be the most sensitive of known cutaneous mechanoreceptors.

  9. 6 Potential Long-Term Effects of Ozempic - AOL

    www.aol.com/6-potential-long-term-effects...

    Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs work by mimicking GLP-1, a hormone naturally produced in the intestines.