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Some sources say insensible losses account for 500 to 650 ml/day (0.5 to 0.6 qt.) of water in adults, [12] [14] while other sources put the minimum value at 800 ml (0.8 qt.). [15] In children, one calculation used for insensible fluid loss is 400 ml/m 2 body surface area. In addition, an adult loses approximately 100 ml/day of fluid through feces.
In the vast majority of species, it eventually becomes differentiated into a dorsal part, connected to the intestine, and a ventral part, associated with the urinogenital passage and urinary bladder. The only mammals in which this does not take place are the platypus and the spiny anteater, both of which retain the cloaca into adulthood. [35]
In the human urinary system there are two kidneys that are located between the dorsal body wall and parietal peritoneum on both the left and right sides. The formation of urine begins within the functional unit of the kidney, the nephrons. Urine then flows through the nephrons, through a system of converging tubules called collecting ducts.
The kidney in humans is capable of producing glucose from lactate, glycerol and glutamine. The kidney is responsible for about half of the total gluconeogenesis in fasting humans. The regulation of glucose production in the kidney is achieved by action of insulin, catecholamines and other hormones. [14]
An estimate of the GFR is used clinically to determine the degree of kidney impairment and to track the progression of the disease. The GFR, however, does not reveal the source of the kidney disease. This is accomplished by urinalysis, measurement of urine protein excretion, kidney imaging, and, if necessary, kidney biopsy. [1]
In multilobar kidneys, the pyramids are separated from each other by dipped into the kidney areas of cortical tissue known as the renal columns. [61] Blood enters the kidney through the renal artery, which in the multilobar kidney then branches in the region of the renal pelvis into large interlobar arteries that pass through the renal columns.
Normally proteins are too large to pass through the kidneys. However they are able to pass through when the glomeruli are damaged. This does not cause symptoms until extensive kidney damage has occurred, [23] after which symptoms include: Foamy or bubbly urine; Swelling in the hands, feet, abdomen, and face; Other symptoms include:
The body stores urine — water and wastes removed by the kidneys — in the urinary bladder, a balloon-like organ. The bladder connects to the urethra, the tube through which urine leaves the body. [21] [citation needed] Continence and micturition involve a balance between urethral closure and detrusor muscle activity (the muscle of the bladder).