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Recent genetic studies have also suggested that some eastern Polynesian populations have admixture from coastal western South American peoples, with an estimated date of contact around 1200 CE. [6] Scientific and scholarly responses to other claims of post-prehistory, pre-Columbian transoceanic contact have varied.
Other serious side effects may include kidney problems, low blood pressure, and angioedema. [8] Use in pregnancy may harm the baby and use when breastfeeding is not recommended. [9] It is an angiotensin II receptor antagonist and works by blocking the effects of angiotensin II. [8] Valsartan was patented in 1990, and came into medical use in ...
1491: New Revelations of the Americas Before Columbus is a 2005 non-fiction book by American author and science writer Charles C. Mann about the pre-Columbian Americas. It was the 2006 winner of the National Academies Communication Award for best creative work that helps the public's understanding of topics in science, engineering or medicine.
Valsartan, telmisartan and EXP 3174 have similar affinities that are about ten-fold less than that of candesartan. Losartan has the least affinity. [ 6 ] ARBs' affinity for the AT 2 receptor is generally much lower (or around 10,000 times less) than for the AT 1 subtype.
Pre-Columbian contact between Alaska and Kamchatka via the subarctic Aleutian Islands would have been conceivable, but the two settlement waves on this archipelago started on the American side and its western continuation, the Commander Islands, remained uninhabited until after Russian explorers encountered the Aleut people in 1741.
Valsartan/hydrochlorothiazide, sold under the brand name Diovan HCT among others, is a medication used to treat high blood pressure when valsartan is not sufficient. [6] It is a combination of valsartan, an angiotensin receptor blocker with hydrochlorothiazide, a diuretic. [7] It is taken by mouth. [7] Common side effects include dizziness and ...
The scientific responses to such pre-Columbian contact claims range from dealing with it in peer-reviewed publications to outright dismissal as fringe science or pseudoarcheology.[3][4]" I am being a pedant here, but as I understand it, there is some mainstream acceptance of North Pacific crossings.
Damaged teeth and bones seem to hold proof of pre-Columbian syphilis, but there is a possibility that they point to an endemic form of treponematosis instead. Some researchers have expressed skepticism regarding whether the cases from Metaponto, Apple Down and Turkey even represent treponemal diseases at all.
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