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MEGA offers support for modifying the genetic code used for translating DNA sequences. By default, MEGA has 23 built-in genetic code variations including the standard code, vertebrate mitochondrial code, Drosophila mitochondrial code, and yeast mitochondrial code. [12] Users may add, remove, or edit any genetic code table.
The starting point, that is the time from which these codes are in effect (usually retroactively), varies from group to group, and sometimes from rank to rank. [7] In botany and mycology, the starting point is often 1 May 1753 (Linnaeus, Species plantarum). In zoology, it is 1 January 1758 (Linnaeus, Systema Naturae, 10th Edition).
The classical table/wheel of the standard genetic code is arbitrarily organized based on codon position 1. Saier, [ 12 ] following observations from, [ 13 ] showed that reorganizing the wheel based instead on codon position 2 (and reordering from UCAG to UCGA) better arranges the codons by the hydrophobicity of their encoded amino acids.
In molecular biology, reading frames are defined as spans of DNA sequence between the start and stop codons. Usually, this is considered within a studied region of a prokaryotic DNA sequence, where only one of the six possible reading frames will be "open" (the "reading", however, refers to the RNA produced by transcription of the DNA and its ...
The coding region of a gene, also known as the coding DNA sequence (CDS), is the portion of a gene's DNA or RNA that codes for a protein. [1] Studying the length, composition, regulation, splicing, structures, and functions of coding regions compared to non-coding regions over different species and time periods can provide a significant amount of important information regarding gene ...
DNA barcoding is a method of species identification using a short section of DNA from a specific gene or genes. The premise of DNA barcoding is that by comparison with a reference library of such DNA sections (also called "sequences"), an individual sequence can be used to uniquely identify an organism to species, just as a supermarket scanner uses the familiar black stripes of the UPC barcode ...
When naming proteins which can be grouped into a family based on homology or according to a notion of shared function (like the interleukins), the different members should be enumerated with a dash "-" followed by an Arabic number, e.g. "desmoglein-1", "desmoglein-2", etc. — "Protein Naming Guidelines".
Edward Hitchcock's fold-out paleontological chart in his 1840 Elementary Geology. Although tree-like diagrams have long been used to organise knowledge, and although branching diagrams known as claves ("keys") were omnipresent in eighteenth-century natural history, it appears that the earliest tree diagram of natural order was the 1801 "Arbre botanique" (Botanical Tree) of the French ...