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There are increased side effects with sublingual or oral misoprostol, compared to a low dose (400 μg) vaginal misoprostol. However, low dose vaginal misoprostol was linked with low complete abortion rate. [42] The study concluded that sublingually administered misoprostol dosed at 600 μg or 400 μg had greater instances of fever and diarrhea ...
Methotrexate is given either orally or intramuscularly, followed by vaginal misoprostol 3–5 days later. [22] The methotrexate combination is available through 63 days. The WHO authorizes the methotrexate-misoprostol combination [ 42 ] but recommends the mifepristone combination because methotrexate may be teratogenic to the embryo in cases of ...
In Great Britain and Sweden, mifepristone is licensed for use with vaginal gemeprost or oral misoprostol. As of 2000, more than 620,000 women in Europe had had medication abortions using a mifepristone regimen. [98] In Denmark, mifepristone was used in between 3,000 and 4,000 of just over 15,000 abortions in 2005. [99]
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Common abortifacients used in performing medical abortions include mifepristone, which is typically used in conjunction with misoprostol in a two-step approach. [3] Synthetic oxytocin , which is routinely used safely during term labor , is also commonly used to induce abortion in the second or third trimester .
For first-trimester abortion, it is dissolved in the cheek or under the tongue; for later abortions, it can also be given as a vaginal suppository. Misoprostol may also be used to ripen the cervix in preparation for surgical abortion. [20] Misoprostol is given orally for the treatment of ulcers.
Prostaglandin E 2 (PGE 2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. [2] [3] [4] Dinoprostone is used in labor induction, bleeding after delivery, termination of pregnancy, and in newborn babies to keep the ductus arteriosus open.
by mouth or orally AMA style avoids use of this abbreviation (spell out "orally") ppt. præparata: prepared p.r., PR per rectum: rectally p.r.n., PRN pro re nata: as needed PRN is pertactin, a virulence factor of the bacterium that causes pertussis: pt. perstetur: continue pulv. pulvis: powder p.v., PV per vaginam: vaginally q quaque: every ...