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Trazodone, sold under many brand names, [1] is an antidepressant medication [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class.
Niaprazine (Nopron) – a drug related to this group but does not inhibit the reuptake of serotonin or the other monoamines. Medifoxamine (Clédial, Gerdaxyl) – could perhaps technically be said to belong to this group, as it is a serotonin–dopamine reuptake inhibitor and 5-HT 2A and 5-HT 2C receptor antagonist , but not grouped as such.
Rare (<0.1%) adverse effects include: Urinary retention; Prolonged QT interval; Torsades de Pointes; Ataxia; Breast enlargement or engorgement; Lactation; Cardiospasm
Other antidepressants, such as bupropion (Wellbutrin), esketamine (Spravato) and trazodone (Desyrel). Our guide to depression medications provides more information on these drugs, how they work ...
Doxepin is a depression medication as well as an effective treatment for lack of sleep and/or anxiety. If you’re struggling with depression, anxiety, insomnia or another issue affecting your ...
[15] A 2019 review stated that "present studies do not suggest the superiority of vilazodone compared with other antidepressants." [16] Development of vilazodone for generalized anxiety disorder has been stopped as of 2017. [17] While there is tentative evidence of a small benefit in generalized anxiety disorder, there is a high rate of side ...
Xywav is a medication used to treat cataplexy or excessive daytime sleepiness. [2] [3] It contains a mixture of the oxybate salts calcium oxybate, magnesium oxybate, potassium oxybate, and sodium oxybate. [2]
In terms of the mechanism of action of benzodiazepines, their similarities are too great to separate them into individual categories such as anxiolytic or hypnotic. For example, a hypnotic administered in low doses produces anxiety-relieving effects, whereas a benzodiazepine marketed as an anti-anxiety drug at higher doses induces sleep. [175]
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