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A meta-analysis showed that supplementation with S. boulardii significantly increased the H. pylori eradication rate and reduced the risk of overall H. pylori therapy-related adverse effects. [12] In a cohort of patients in Korea who received S. boulardii for 4 weeks during and after a 1-week course of standard triple therapy, eradication rates ...
Saccharomyces boulardii is a tropical yeast first isolated from lychee and mangosteen peels in 1923 by French scientist Henri Boulard. Although early reports claimed distinct taxonomic , metabolic, and genetic properties, [ 1 ] S. boulardii is a grouping of S. cerevisiae strains, all sharing a >99% genomic relatedness.
Henri Boulard was a French microbiologist who discovered the yeast Saccharomyces boulardii in 1923. He noticed people chewing on the skins of lychees and mangosteens to treat diarrhea during a cholera epidemic. He isolated and identified this strain of yeast, a probiotic. [1]
H pylori is a helical bacterium having a predominantly helical shape, also often described as having a spiral or S shape. [24] [25] Its helical shape is better suited for progressing through the viscous mucosa lining of the stomach, and is maintained by a number of enzymes in the cell wall's peptidoglycan. [1]
Several anti-ulcer dosing regimens that combine antibiotics and proton pump inhibitors (PPI) to treat helicobacter pylori (H. pylori) induced peptic ulcer disease (PUD). The role of antibiotic in the therapies is to eradicate H. pylori, while the action of PPI is to reduce gastric acid secretion. The anti-ulcer dosing regimens generally repair ...
The European Helicobacter Pylori Study Group published the Maastricht 2-2000 Consensus Report, suggesting a "test-and-treat" strategy for H. pylori in young patients without atypical symptoms. This strategy advocates the use of noninvasive testing to evaluate for H. pylori and simply treating if found, even in the absence of ulcer disease ...
Conversely, Lactobacillus fermentum and Saccharomyces boulardii have been found to be ineffective. [4] [failed verification] A combination of Lactobacillus plantarum and Lactobacillus rhamnosus has been found to be effective in suppressing bacterial overgrowth of abnormal gas producing organisms in the small intestine. [32] [non-primary source ...
The strain Saccharomyces cerevisiae var. boulardii is industrially manufactured and used clinically as a medication. Several clinical and experimental studies have shown that S. cerevisiae var. boulardii is, to lesser or greater extent, useful for prevention or treatment of several gastrointestinal diseases. [71]
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