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The most frequent cause of autosplenectomy is sickle cell anemia [10] which causes progressive splenic hypofunction over time. Increased deoxygenation causes sickling of red blood cells, which adhere to the spleen wall and splenic macrophages causing ischemia . [ 2 ]
The classical cause of traumatic damage to the spleen is a blow to the abdomen during a sporting event. In cases where the spleen is enlarged due to illness (mononucleosis), trivial activities, such as leaning over a counter or straining while defecating, can cause a rupture.
Conditions such as sleep apnea, hypothyroidism, and depression can hinder weight loss and cause weight gain, according to WebMD. "Many medical conditions are associated with weight gain, so it's ...
12 Common Causes of Sudden Weight Gain You’re eating too much salt. Sodium consumption causes your body to retain water. Water has weight and volume. So if you eat a lot of salty food several ...
Due to underlying diseases that destroy the spleen (autosplenectomy), e.g. sickle-cell disease. Celiac disease: unknown physiopathology. [6] In a 1970 study, [7] it was the second most common cause of abnormalities of red blood cells linked to hyposplenism, after surgical splenectomy.
Specifically, studies suggest that muscle loss with GLP-1s can range from 25 to 39 percent of the total weight loss while muscle loss via caloric restriction (with less total weight loss) ranges ...
Spleens are also removed for therapeutic purposes in conditions like hereditary spherocytosis, trauma to the spleen, and autosplenectomy caused by sickle cell anemia. Other causes are radiation therapy involving the spleen, such as that used to treat Hodgkin lymphoma. Howell–Jolly bodies inside of two normoblasts (center) in bone marrow ...
Potential Causes and Side Effects. ... and it found that those who slept over 10 hours were 21 percent more likely to gain weight than those who slept seven to nine hours a night. In other words ...