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IPEX is caused by mutations in the gene FOXP3, which encodes transcription factor forkhead box P3 . FOXP3 is widely considered to be the master regulator of the regulatory T cell (Treg) lineage. [6] [7] FOXP3 mutation can lead to the dysfunction of CD4 + Tregs. In healthy people, Tregs maintain immune homeostasis. [8]
IPEX may refer to: Immunodysregulation polyendocrinopathy enteropathy X-linked syndrome, a rare disease linked to the dysfunction of the transcriptional activator FoxP3; Italian Power Exchange; Interparliamentary EU Information Exchange; IPEX (trade show), the largest printing and graphic arts trade show in the English-speaking world
IPEX came about as the result of a recommendation made by the Conference of the Speakers of the European Union Parliaments [4] in Rome in 2000. In accordance with the Guidelines for interparliamentary cooperation Archived 2012-04-03 at the Wayback Machine, agreed in The Hague in 2004, the official launch of the website took place in June 2006 during the EU Speakers Conference in Copenhagen. [5]
J-List is an online retailer of Japanese goods for consumers outside Japan, mainly otaku goods, anime, and manga. [1] The company was established by American Peter Payne [2] in 1996.
The demise of Ipex came thanks to an ill-fated decision to switch the location for the 2014 show from the NEC, with its ultra-easy air, rail and road access, and very pleasant surrounds in Shakespeare country, to a somewhat inaccessible location in east London, the Excel Centre, with its tortuous road and rail links.
Introduced to North America on 9 September 1991, the XV10 Camry was sold alongside the V30 in Japan, badged as the Toyota Scepter. [9] Toyota chose the name "Scepter" as a reference to the Camry/Crown naming tradition, as a "scepter" is a symbolic ornamental staff held by a ruling monarch, a prominent item of royal regalia.
A Casio G-Shock GW-9200J "Riseman" watch incorporating Multi-band 6 technology. Casio Multi-Band 6 watches can tune to any of the six signals of the low frequency radio time signals. [4] [5] Some of the Casio G-Shock line of watches have Multi-Band 6 technology. The earlier Multi-Band 5 system could not receive the signal of the Chinese time ...
Sceptre was a series of early fusion power devices based on the Z-pinch concept of plasma confinement, built in the UK starting in 1956. They were the ultimate versions of a series of devices tracing their history to the original pinch machines, built at Imperial College London by Cousins and Ware in 1947.