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o-Toluidine is absorbed through inhalation and dermal contact as well as from the gastrointestinal tract. [19] [13] [20] [21]The metabolism of o-toluidine involves many competing activating and deactivating pathways, including N-acetylation, N-oxidation, and N-hydroxylation, and ring oxidation.
2-Tolidine (orthotolidine, o-tolidine; not to be confused with o-toluidine) is an organic compound with the chemical formula (C 6 H 4 (CH 3)NH 2) 2. Several isomers are known; the 3-tolidine derivative is also important commercially. It is a colorless compound although commercial samples are often colored. It is slightly soluble in water.
Ichthammol or ammonium bituminosulfonate (brand name Ichthyol), also known as black ointment, is a medication derived from sulfur-rich oil shale (bituminous schists). It is used (sometimes in combination with zinc oxide) as a treatment for different skin diseases, including eczema and psoriasis (see below).
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
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Hunter Steinitz (born October 17, 1994) as of June 2010 was 16 and one of only twelve Americans living with the disease, and was profiled on National Geographic's "Extraordinary Humans: Skin" special. [37] Mui Thomas (born in 1992 in Hong Kong) was 24 as of 2016 and qualified as the first rugby referee with harlequin ichthyosis. [38]
Rodent mite dermatitis (also known as rat mite dermatitis) is an often unrecognized ectoparasitosis occurring after human contact with haematophagous mesostigmatid mites that infest rodents, such as house mice, [1] rats [2] and hamsters. [3]
Uses include for fungal infections of the foot, impetigo, pemphigus, superficial wounds, dermatitis (eczema), and tropical ulcers. [3] [2] Typically it is used in skin conditions that produce a lot of liquid. [3] For tropical ulcers it is used together with procaine benzylpenicillin for two to four weeks. [2] [8] It can be used in children and ...