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  2. Drugs for acid-related disorders - Wikipedia

    en.wikipedia.org/wiki/Drugs_for_acid-related...

    The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.

  3. Anti-ulcer agents - Wikipedia

    en.wikipedia.org/wiki/Anti-ulcer_agents

    An anti-ulcer medication for treating mouth ulcer is triamcinolone, a corticosteroid. Other anti-ulcer supplements include vitamin B2 and vitamin B12 . Antibiotics and agents to reduce gastric acid secretion are used in combinations to treat Helicobacter pylori ( H. pylori )-induced peptic ulcer disease (PUD), an ulceration in the gastric region.

  4. Vonoprazan - Wikipedia

    en.wikipedia.org/wiki/Vonoprazan

    Vonoprazan, sold under the brand name Voquezna among others, is a first-in-class potassium-competitive acid blocker medication. [2] [1] Vonoprazan is used in form of the fumarate for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of Helicobacter pylori.

  5. H2 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H2_receptor_antagonist

    Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.

  6. Zastaprazan - Wikipedia

    en.wikipedia.org/wiki/Zastaprazan

    Zastaprazan (trade name Jaqbo) is a pharmaceutical drug for gastrointestinal disorders.It is classified as a potassium-competitive acid blocker. [1] [2] In April 2024, it was approved for use in South Korea for the treatment of erosive gastroesophageal reflux disease (GERD). [3]

  7. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Proton pump inhibitors (PPIs) block the gastric hydrogen potassium ATPase (H + /K + ATPase) and inhibit gastric acid secretion. These drugs have emerged as the treatment of choice for acid-related diseases, including gastroesophageal reflux disease (GERD) and peptic ulcer disease. PPIs also can bind to other types of proton pumps such as those ...

  8. Pirenzepine - Wikipedia

    en.wikipedia.org/wiki/Pirenzepine

    Pirenzepine (Gastrozepin), an M 1 selective antagonist, is used in the treatment of peptic ulcers, as it reduces gastric acid secretion and reduces muscle spasm.It is in a class of drugs known as muscarinic receptor antagonists; acetylcholine is the neurotransmitter of the parasympathetic nervous system which initiates the rest-and-digest state (as opposed to fight-or-flight), resulting in an ...

  9. Ilaprazole - Wikipedia

    en.wikipedia.org/wiki/Ilaprazole

    Ilaprazole (trade name Noltec) is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) [1] and duodenal ulcer. [2] [3] It is available in strengths of 5, 10, and 20 mg.

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