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One of the important questions in sleep research is clearly defining the sleep state. This problem arises because sleep was traditionally defined as a state of consciousness and not as a physiological state, [14] [15] thus there was no clear definition of what minimum set of events constitute sleep and distinguish it from other states of partial or no consciousness.
Sleep deprivation also has a documented effect on the ability to acquire new memories for subsequent consolidation. A study done on mice that were sleep deprived before learning a new skill but allowed to rest afterward displayed a similar number of errors on later trials as the mice that were sleep deprived only after the initial learning. [46]
Studies in sleep-deprived rats have found a decrease in acetylated histones at the BDNF promoter IV, which is crucial for learning and memory. Models disrupting the sleep-wake cycle in flies and models of neurodegenerative diseases suggest that decreased histone acetylation is associated with neuronal dysfunction.
Matthew Walker is a British author, scientist and professor of neuroscience and psychology at the University of California, Berkeley. [1] [3] [4] [5] As an academic, Walker has focused on the impact of sleep on human health. He has contributed to many scientific research studies. [1] Why We Sleep (2017) is his first work of popular science. [6]
"An Essay on Consciousness". in Teaching of Psychology 8(1):15-19 · February 1981 "Sleep and Sleeplessness in Advanced Age, Vol. 5". Advances in Sleep Research. in PsycCRITIQUES 26(10) · January 1981 "In pursuit of the shiftworker: A discussion of methodologies". in Behavior Research Methods 11(1):24-25 · January 1979
Sleep is a monthly peer-reviewed medical journal covering research on sleep. Topics include basic and neuroscience studies of sleep, in vitro and animal models of sleep, studies in clinical or population samples, clinical trials, and epidemiologic studies. It is the official journal of the Sleep Research Society.
After going through stages of REM-sleep, people with depression report feeling better, in a study done by Cartwright et al. [40] Conversely, a theory proposed by Revonsuo [41] states that when people experience negative emotions or negative events, when they sleep the REM-sleep replays such events, which is known as rehearsal. [39]
Mary A. Carskadon is an American sleep researcher. She is a professor in the Department of Psychiatry and Human Behavior at the Warren Alpert Medical School of Brown University, and the director of the Sleep and Chronobiology Research Lab at E.P. Bradley Hospital.