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  2. Immortalised cell line - Wikipedia

    en.wikipedia.org/wiki/Immortalised_cell_line

    An immortalised cell line is a population ... but form a normal part of the development of a ... for the analysis of the biochemistry and cell biology of mammalian ...

  3. Chinese hamster ovary cell - Wikipedia

    en.wikipedia.org/wiki/Chinese_hamster_ovary_cell

    CHO cells adhered to a surface, seen under phase-contrast microscopy. Chinese hamster ovary (CHO) cells are a family of immortalized cell lines [1] derived from epithelial cells of the ovary of the Chinese hamster, often used in biological and medical research and commercially in the production of recombinant therapeutic proteins.

  4. Cell culture - Wikipedia

    en.wikipedia.org/wiki/Cell_culture

    Many methods are used to identify cell lines, including isoenzyme analysis, human lymphocyte antigen (HLA) typing, chromosomal analysis, karyotyping, morphology and STR analysis. [35] One significant cell-line cross contaminant is the immortal HeLa cell line. HeLa contamination was first noted in the early 1960s in non-human culture in the USA.

  5. HeLa - Wikipedia

    en.wikipedia.org/wiki/HeLa

    The story of how the HeLa cell line came to be was also the subject of a 2010 episode of the podcast Radiolab. [69] HeLa cells were the subject of a 2010 book by Rebecca Skloot, The Immortal Life of Henrietta Lacks, investigating the historical context of the cell line and how the Lacks family was involved in its use. [14]

  6. HEK 293 cells - Wikipedia

    en.wikipedia.org/wiki/HEK_293_cells

    Human embryonic kidney 293 cells, also often referred to as HEK 293, HEK-293, 293 cells, are an immortalised cell line derived from HEK cells isolated from a female fetus in the 1970s. [ 1 ] [ 2 ] The HEK 293 cell line has been widely used in research for decades due to its reliable and fast growth and propensity for transfection .

  7. Germline development - Wikipedia

    en.wikipedia.org/wiki/Germline_development

    [citation needed] Spermatogenic cells at different stages of development in the mouse have a frequency of mutation that is 5 to 10-fold lower than the mutation frequency in somatic cells. [46] In Drosophila, the ability of premeiotic male germ line cells to repair double-strand breaks declines dramatically with age. [47]

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