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One way depression increases the individual's focus on a problem is by inducing rumination. Depression activates the left ventrolateral prefrontal cortex, which increases attention control and maintains problem-related information in an "active, accessible state" referred to as "working memory", or WM. As a result, depressed individuals have ...
This region is extremely rich in serotonin transporters and is considered as a governor for a vast network involving areas like hypothalamus and brain stem, which influences changes in appetite and sleep; the amygdala and insula, which affect the mood and anxiety; the hippocampus, which plays an important role in memory formation; and some ...
Epigenetics of depression is the study of how epigenetics (heritable characteristics that do not involve changes in DNA sequence) contribute to depression. Major depressive disorder is heavily influenced by environmental and genetic factors.
Evolutionary psychiatry, also known as Darwinian psychiatry, [1] [2] is a theoretical approach to psychiatry that aims to explain psychiatric disorders in evolutionary terms. [3] [4] As a branch of the field of evolutionary medicine, it is distinct from the medical practice of psychiatry in its emphasis on providing scientific explanations rather than treatments for mental disorder.
This suggests that antidepressants need to affect other biological systems, apart from monoamines, in order to reduce depressive symptoms. Relationship between neurogenesis and depression. Stress has been reported to impair many aspects of hippocampal neurogenesis, including: [3] Proliferation rate of neural progenitor cells
Six subtypes of major depression have been identified in a new study. Here’s what that could mean for the future of personalized mental health care. A study identified 6 types of depression.
The neurotrophic hypothesis of depression [1] proposes that major depressive disorder (MDD) is caused, at least partly, by impaired neurotrophic support.Neurotrophic factors (also known as neurotrophins) are a family of closely related proteins which regulate the survival, development, and function of neurons in both the central and peripheral nervous systems.
The mechanism of long-term depression has been well characterized in limited parts of the brain. However, the way in which LTD affects motor learning and memory is still not well understood. Determining this relationship is presently one of the major focuses of LTD research.