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Diarrhea is a well-known side effect of metformin. Learn more about why this gut-related side effect happens and how to manage it. Does Metformin Cause Diarrhea?
The most common side effects of metformin include: Diarrhea. Nausea. Vomiting. ... Prepare for potential side effects. Taking metformin may cause unpleasant side effects like diarrhea, nausea, and ...
The medication most commonly may cause stomach upset and symptoms such as diarrhea but in general is well tolerated and has a relatively low chance of causing hypoglycemia. [35] One rare (about 1% chance) but serious side affect of metformin is that it can cause lactic acidosis, usually in patients with poor kidney function. [35]
Metformin is a pleiotropic drug, with extensive off-target activity beyond its antidiabetic effect. Much of this has been attributed to its action on AMPK, although other mechanisms have been proposed. [221] [222] Metformin has been studied for its effects on multiple other conditions, including: Non-alcoholic fatty liver disease [223] [224] [225]
Postcholecystectomy diarrhea is diarrhea that occurs following gall bladder removal, due to excess bile acid. [21] Orlistat is an anti-obesity (weight loss) drug that blocks the absorption of fats. This may give side effects of FI, diarrhea, and steatorrhea. [22]
One theory is that metformin has anti-tumor side effects because it lowers insulin levels and keeps tumor cells from multiplying. Still, more research is needed. Inside Creative House/istockphoto
A persistent (chronic) history of diarrhea, with watery or mushy, unformed stools, (types 6 and 7 on the Bristol stool scale), sometimes with steatorrhea, increased frequency and urgency of defecation are common manifestations, often with fecal incontinence and other gastrointestinal symptoms such as abdominal swelling, bloating and abdominal pain.
Diarrhea (American English), also spelled diarrhoea or diarrhœa (British English), is the condition of having at least three loose, liquid, or watery bowel movements in a day. [2] It often lasts for a few days and can result in dehydration due to fluid loss. [2]