Search results
Results from the WOW.Com Content Network
Methanesulfonyl chloride is mainly used to give methanesulfonates by its reaction with alcohols in the presence of a non-nucleophilic base. [8] In contrast to the formation of toluenesulfonates from alcohols and p-toluenesulfonyl chloride in the presence of pyridine, the formation of methanesulfonates is believed to proceed via a mechanism wherein methanesulfonyl chloride first undergoes an ...
Sulfonation of chlorobenzene resulted in addition of methylsulfonyl group at para and ortho positions (with respect to chloride), with a ratio of 2 to 1, respectively; while reaction with Meta-dichlorobenzene gave monosulfonylated product at C4 position. [8] With sulfuric acid, di-aryl sulfones were synthesized. [9]
633.4 K (360.25°C), 4.52 MPa Std enthalpy change of fusion, Δ fus H o? kJ/mol Std entropy change of fusion, Δ fus S o: 9.6 J/(mol·K) Std enthalpy change of vaporization, Δ vap H o: 40.97 kJ/mol Std entropy change of vaporization, Δ vap S o? J/(mol·K) Solid properties Std enthalpy change of formation, Δ f H o solid? kJ/mol Standard molar ...
Tosyl chloride (p-toluenesulfonyl chloride) CH 3 C 6 H 4 SO 2 Cl Brosyl: p-bromobenzenesulfonyl Bs Nosyl o- or p-nitrobenzenesulfonyl Ns Mesyl: methanesulfonyl Ms Mesyl chloride (methanesulfonyl chloride) CH 3 SO 2 Cl Triflyl: trifluoromethanesulfonyl Tf Tresyl: 2,2,2-trifluoroethyl-1-sulfonyl Dansyl: 5-(dimethylamino)naphthalene-1-sulfonyl Ds ...
In chemistry, a sulfonyl halide consists of a sulfonyl (>S(=O) 2) group singly bonded to a halogen atom. They have the general formula RSO 2 X, where X is a halogen.The stability of sulfonyl halides decreases in the order fluorides > chlorides > bromides > iodides, all four types being well known.
The chloride substituent in 4-nitrochlorobenzene is more labile than in chlorobenzene. For example, it is readily displaced by sulfide nucleophiles, leading the way to 4-nitrothiophenol. [4] In another example, 4-nitrochlorobenzene is a favored substrate for cross-coupling reactions. [5]
4,4’-Dichlorobenzophenone is prepared by the acylation of chlorobenzene with 4-chlorobenzoyl chloride. The conversion is typically conducted in the presence of an aluminium chloride catalyst in a petroleum ether solvent. ClC 6 H 5 C(O)Cl + C 6 H 5 Cl → (ClC 6 H 4) 2 CO + HCl
Methanesulfonyl chloride is often referred to as mesyl chloride. Whereas mesylates are often hydrolytically labile, mesyl groups, when attached to nitrogen , are resistant to hydrolysis. [ 5 ] This functional group appears in a variety of medications, particularly cardiac ( antiarrhythmic ) drugs, as a sulfonamide moiety.