Search results
Results from the WOW.Com Content Network
Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
Is the polio vaccine safe? While an oral polio vaccine (OPV) is administered in some countries, inactivated polio vaccine (IPV) has been the only available form of immunization in the U.S. since 2000.
Two vaccines are used throughout the world to combat poliomyelitis.The first, a polio vaccine developed by Jonas Salk, is an inactivated poliovirus vaccine (IPV), consisting of a mixture of three wild, virulent strains of poliovirus, grown in a type of monkey kidney tissue culture (Vero cell line), and made noninfectious by formaldehyde treatment.
Many countries began polio immunization campaigns using Salk's vaccine, including Canada, Sweden, Denmark, Norway, West Germany, the Netherlands, Switzerland, and Belgium. By 1959, the Salk vaccine had reached about 90 countries. [5] An attenuated live oral polio vaccine was developed by Albert Sabin, coming into commercial use in 1961. Less ...
The recent New York patient was infected with vaccine-derived polio, a strain linked to live virus from an oral polio vaccine not administered in the U.S. It marks the first U.S. of vaccine ...
The polio vaccine is given as part of routine childhood immunizations. The series of four doses total starts at age 2 months, followed by one dose at age 4 months, another dose at 6 to 18 months ...
The vaccine derived from this strain, novel oral polio virus type 2 (nOPV2), was granted emergency licencing in 2021, and subsequently full licensure in December 2023. [75] Genetically stabilsed vaccines targeting poliovirus types 1 and 3 are in development, with the intention that these will eventually completely replace the Sabin vaccines. [76]
Polio has existed for centuries; ancient Egyptian hieroglyphics show children walking with canes, with the wasted limbs characteristic of polio victims. Before the first vaccine was developed in ...