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The Thorough QT/QTc study was designed to assess the effect on the QT/QTc interval, both of the therapeutic dose (20 mg) and 100 mg of bilastine, but also the coadministration of the therapeutic dose with usual doses of ketoconazol (400 mg/day), a metabolism inhibitor and a P-gP dependent transport system.
Ebastine is a second-generation H1 receptor antagonist that is indicated mainly for allergic rhinitis and chronic idiopathic urticaria. [5] It is available in 10 and 20 mg tablets [6] and as fast-dissolving tablets, [7] as well as in pediatric syrup. It has a recommended flexible daily dose of 10 or 20 mg, depending on disease severity.
Solifenacin, sold as the brand name Vesicare[a] among others, is a medicine used to treat overactive bladder and neurogenic detrusor overactivity (NDO). [1][2] It may help with incontinence, urinary frequency, and urinary urgency. [3] Benefits appear similar to other medications in the class. [4] It is taken by mouth.
Fexofenadine, sold under the brand name Allegra among others, [10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria. [11] Therapeutically, fexofenadine is a selective peripheral H 1 blocker.
Mianserin, sold under the brand name Tolvon among others, is an atypical antidepressant that is used primarily in the treatment of depression in Europe and elsewhere in the world. [6] It is a tetracyclic antidepressant (TeCA).
In the United States and Canada, clorazepate is available in 3.75, 7.5, and 15 mg capsules or tablets. In Europe, tablet formations are 5 mg, 10 mg, 20 mg and 50 mg. [6] Clorazepate SD (controlled release) is available and may have a reduced incidence of adverse effects. The sustained-release formulation of clorazepate has some advantages in ...
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Fluphenazine. Fluphenazine, sold under the brand name Prolixin among others, is a high-potency typical antipsychotic medication. [2] It is used in the treatment of chronic psychoses such as schizophrenia, [2][3] and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine. [4]
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