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Voriconazole, sold under the brand name Vfend among others, is an antifungal medication used to treat a number of fungal infections. [5] This includes aspergillosis , candidiasis , coccidioidomycosis , histoplasmosis , penicilliosis , and infections by Scedosporium or Fusarium . [ 5 ]
European Union: In the EU, Good Clinical Practice is backed and regulated by formal legislation contained in the Clinical Trial Regulation (Officially Regulation (EU) No 536/2014 of the European Parliament and of the Council of 16 April 2014 on clinical trials on medicinal products for human use, and repealing Directive 2001/20/EC). [3]
The 71st Edition, published in 2017, was the final hardcover edition, weighed in at 4.6 pounds (2.1 kg) and contained information on over 1,000 drugs. [1] Since then, the PDR has been available online for free. The Physicians' Desk Reference was first published in 1947 by Medical Economics Inc., a magazine publisher founded by Lansing Chapman. [2]
The WHO Model List of Essential Medicines for Children (aka Essential Medicines List for Children [1] or EMLc [1]), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe in children up to twelve years of age to meet the most important needs in a health system.
[1] Some fungi (e.g. Candida krusei and fluconazole ) exhibit intrinsic resistance to certain antifungal drugs or classes, whereas some species develop antifungal resistance to external pressures. Antifungal resistance is a One Health concern, driven by multiple extrinsic factors, including extensive fungicidal use, overuse of clinical ...
Comparable sales: up 0.3% year over year, vs. 1.48% estimate (last year comparable sales fell 4.9%; Walmart US reported a 5.3% gain in the third quarter of 2024) Digital comparable sales: up 10.8% ...
From June 2008 to December 2012, if you bought shares in companies when Gregory B. Penner joined the board, and sold them when he left, you would have a 16.9 percent return on your investment, compared to a 4.8 percent return from the S&P 500.
[1] A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life . Such drugs need only a low maintenance dose in order to keep the amount of the drug in the body at the appropriate therapeutic level , but this also means that, without an initial higher dose, it would take a ...