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Beta-blockers with intrinsic sympathomimetic activity: acebutolol, pindolol; Some common side effects include increased airway resistance for non-selective beta-blockers, exacerbation of peripheral vascular diseases, and hypotension [15] Beta-blockers are contraindicated in patients with second- or third-degree atrioventricular block.
Beta blockers, due to their antagonism at beta-1 adrenergic receptors, inhibit both the synthesis of new melatonin and its secretion by the pineal gland. The neuropsychiatric side effects of some beta blockers (e.g. sleep disruption, insomnia) may be due to this effect. [99]
Landiolol, sold under the brand name Onoact among others, is a medication used for the treatment of tachycardia, atrial fibrillation, and atrial flutter. [1] [4] It is a beta-adrenergic blocker; [4] an ultra short-acting, β1-superselective intravenous adrenergic antagonist, which decreases the heart rate effectively with less negative effect on blood pressure or myocardial contractility.
The cardio-selective beta-1 blockers could cause adverse effects including bradycardia, reduced exercise ability, hypotension, atrioventricular nodal blockage and heart failure. [5] Other possible adverse effects include nausea and vomiting , abdominal discomfort , dizziness , weakness , headache , fatigue , and dryness in mouth and eye . [ 5 ]
Selective beta 1 blockers have been shown to have an array of cardiac common side effects, comprising bradycardia, reduced exercise tolerance, hypotension, atrioventricular block, and heart failure. [4] Regarding non-cardiac side effects, they can cause nausea, headache, fatigue, dry mouth, and dry eyes. [4]
Common side effects include nausea, abdominal pain, and constipation. [2] It may worsen the symptoms of asthma. [2] Propranolol may cause harmful effects for the baby if taken during pregnancy; [7] however, its use during breastfeeding is generally considered to be safe. [8] It is a non-selective beta blocker which works by blocking β ...
Side effects are similar to those of other beta blockers, such as bronchoconstriction, cardiac failure, cold extremities, fatigue and depression, hypoglycaemia. [ 4 ] Furthermore, chronic use of practolol may cause oculomucocutaneous syndrome , [ 4 ] a severe syndrome whose signs include conjunctivitis sicca and psoriasiform rashes , otitis and ...
Esmolol is classified as a beta blocker with low lipophilicity and hence lower potential for crossing the blood–brain barrier. [8] This in turn may result in fewer effects in the central nervous system as well as a lower risk of neuropsychiatric side effects. [8]
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