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Hypoxic ventilatory response (HVR) is the increase in ventilation induced by hypoxia that allows the body to take in and transport lower concentrations of oxygen at higher rates. It is initially elevated in lowlanders who travel to high altitude, but reduces significantly over time as people acclimatize .
A controlled F I O 2 is particularly important for patients whose ventilation is dependent on hypoxic drive, [5] as may be seen in patients with chronic obstructive pulmonary disease. Administration of too much oxygen may lead to a reduction in their respiratory rate and retention of carbon dioxide, and ultimately to reduced consciousness or ...
The control of ventilation is the physiological mechanisms involved in the control of breathing, which is the movement of air into and out of the lungs. Ventilation facilitates respiration. Respiration refers to the utilization of oxygen and balancing of carbon dioxide by the body as a whole, or by individual cells in cellular respiration. [1]
Hypoxic air systems can be integrated with the building management system and can include systems to recover the heat generated by the hypoxic air generator that, would otherwise be wasted. [ 5 ] Air with low oxygen concentration is transported to the protected volumes through dedicated pipes or, more simply, via an existing ventilation system .
The volume-cycled ventilation is the simplest and most efficient of providing ventilation to a patient's airway compared to other methods of mechanical ventilation. Each inspiratory effort that is beyond the set sensitivity threshold will be accounted for and fixed to the delivery of the corresponding tidal volume.
Many people with chronic obstructive pulmonary disease have a low partial pressure of oxygen in the blood and high partial pressure of carbon dioxide.Treatment with supplemental oxygen may improve their well-being; alternatively, in some this can lead to the adverse effect of elevating the carbon dioxide content in the blood (hypercapnia) to levels that may become toxic.
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Because the brain stem regulates breathing by monitoring the level of blood CO 2 instead of O 2, hypocapnia can suppress breathing to the point of blackout from cerebral hypoxia, as exhibited in shallow water blackout. Hypocapnia also results in bronchoconstriction [3] in order to decrease ventilation. This mechanism is meant to counteract ...
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