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MDAI, also known as 5,6-methylenedioxy-2-aminoindane, is an entactogen drug of the 2-aminoindane group which is related to MDMA and produces similar subjective effects. [ 4 ] [ 5 ] [ 6 ] [ 1 ] It acts as a selective serotonin and norepinephrine releasing agent (SNRA). [ 2 ]
A recreational dose of MDA is sometimes cited as being between 100 and 160 mg. [7] Overdose. Symptoms of acute toxicity may include agitation, ... MDAI: 114: 117: 1,334
MDI canister and actuator components from H&T Presspart. A metered-dose inhaler consists of three major components: the canister, which is produced in aluminum or stainless steel by means of deep drawing, where the formulation resides; the metering valve, which allows a metered quantity of the formulation to be dispensed with each actuation; and an actuator (or mouthpiece) which enables the ...
The human dosage of 5-IAI has been described as 100 to 200 mg and its duration of action as 2 to 4 hours. [2] Human anecdotal reports suggest that 5-IAI is entactogenic and that it increases sociability and trust. [2] On the other hand, it is reported that 5-IAI produces very little euphoria and is far less stimulating than MDMA and other ...
3,4-Dihydroxymethamphetamine (HHMA, 3,4-DHMA), or 3,4-dihydroxy-N-methylamphetamine, also known as α-methylepinine or α,N-dimethyldopamine, is the major metabolite of 3,4-methylenedioxy-N-methylamphetamine (MDMA).
[38] [40] [39] [41] It has been said by Matthew Baggott that few to no MDMA analogues, including MBDB, methylone, 6-APDB, 5-APDB, 6-APB, 5-APB, MDAT, and MDAI among others, reproduce the full quality and "magic" of MDMA. [40] [42] Exceptions may anecdotally include 5-MAPB, particularly in specific enantiomer ratios, and the Borax combo.
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MDAI suppresses locomotor activity initially, but there is rebound locomotor stimulation at a high dose, and this was similar to the profile of MDMA. [41] [42] The increased locomotion induced by SRAs that cause this effect appears to be critically dependent on serotonin 5-HT 1B receptor signaling.