Search results
Results from the WOW.Com Content Network
MDAI, also known as 5,6-methylenedioxy-2-aminoindane, is an entactogen drug of the 2-aminoindane group which is related to MDMA and produces similar subjective effects. [ 4 ] [ 5 ] [ 6 ] [ 1 ] It acts as a selective serotonin and norepinephrine releasing agent (SNRA). [ 2 ]
Activities of 2-aminoindanes and amphetamine relatives; Compound Monoamine release (EC 50 Tooltip half-maximal effective concentration, nM) Ref Serotonin Norepinephrine Dopamine; 2-AI
An assortment of several designer drugs. Designer drugs are structural or functional analogues of controlled substances that are designed to mimic the pharmacological effects of the parent drug while avoiding detection or classification as illegal.
Scientists performed a study on NM2AI metabolism in silico and in vivo, in order to identify the main metabolites to be screened in the different biological samples.They performed the in silico metabolism prediction of NM2AI using MetaSiteTM software and subsequently verified the presence of metabolites in the blood, urine and hair of mice after NM-2-AI administration.
Unlike related 2-aminoindane derivatives like MDAI and MMAI, 5-IAI causes some serotonergic neurotoxicity in rats (15% or less reduction of serotonergic markers), but is less neurotoxic than its corresponding amphetamine homologue para-iodoamphetamine (pIA) and the doses employed have been described as "extremely high".
5-Methoxy-6-methyl-2-aminoindane (MMAI) is a drug of the 2-aminoindane group developed in the 1990s by a team led by David E. Nichols at Purdue University. [1] It acts as a less neurotoxic and highly selective serotonin releasing agent (SSRA) and produces entactogenic effects in humans.
Poker: Texas Hold'em (No Limit) Play two face down cards and the five community cards. Bet any amount or go all-in. By Masque Publishing
3,4-Methylenedioxyamphetamine (MDA), sometimes referred to as sass, is an empathogen-entactogen, stimulant, and psychedelic drug of the amphetamine family that is encountered mainly as a recreational drug.