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This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Possible side effects include itching, rash, infusion-related reactions, nausea and vomiting. [ 2 ] Bebtelovimab works by binding to the spike protein of the virus that causes COVID-19, similar to other monoclonal antibodies that have been authorized for the treatment of high-risk people with mild to moderate COVID-19 and shown a benefit in ...
Sotrovimab, sold under the brand name Xevudy, is a human neutralizing monoclonal antibody with activity against severe acute respiratory syndrome coronavirus 2, known as SARS-CoV-2. [ 10 ] [ 12 ] [ 13 ] It was developed by GlaxoSmithKline and Vir Biotechnology, Inc. [ 12 ] [ 14 ] Sotrovimab is designed to attach to the spike protein of SARS-CoV-2.
Omicron has rendered most monoclonal antibodies useless at treating disease, but one is still effective What to Know About Monoclonal Antibodies as COVID-19 Treatments Skip to main content
The U.S. Food & Drug Administration granted emergency-use authorization last year. Some hospitals don't offer monoclonal antibodies to fight COVID-19.
The most common side effects include allergic reactions, which include infusion related reactions, injection site reactions, [10] brief pain, weakness and others. [17] The combination is approved under the brand name Ronapreve for medical use in Japan, the United Kingdom, the European Union, and Australia. [1] [7] [10] [12] [18] [19]
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Tocilizumab, sold under the brand name Actemra among others, is an immunosuppressive drug, used for the treatment of rheumatoid arthritis, systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, giant cell arteritis, cytokine release syndrome, COVID‑19, and systemic sclerosis-associated interstitial lung disease (SSc-ILD).
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