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  2. Directionality (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Directionality_(molecular...

    The 3′-end (three prime end) of a strand is so named due to it terminating at the hydroxyl group of the third carbon in the sugar-ring, and is known as the tail end. The 3′-hydroxyl is necessary in the synthesis of new nucleic acid molecules as it is ligated (joined) to the 5′-phosphate of a separate nucleotide, allowing the formation of ...

  3. Rolling hairpin replication - Wikipedia

    en.wikipedia.org/wiki/Rolling_hairpin_replication

    A 3′ hydroxyl end of the left-hand (3′) terminus pairs with an internal base to prime initial DNA synthesis, resulting in the conversion of the ssDNA genome to its first duplex form. [ 1 ] [ 7 ] This is a monomeric double-stranded DNA molecule in which the two strands are covalently cross-linked to each other at the left-end by a single ...

  4. Parvoviridae - Wikipedia

    en.wikipedia.org/wiki/Parvoviridae

    The 3′-end (usually pronounced "three prime end") of a negative sense strand, and the 5′-end (usually pronounced "five prime end") of a positive sense strand, is called the left end, and the 5′-end of the negative sense strand, and the 3′-end of a positive sense strand, is called the right end. [2] [4] [5]

  5. Subgenomic mRNA - Wikipedia

    en.wikipedia.org/wiki/Subgenomic_mRNA

    During transcription, the original template strand is usually read from the 3' to the 5' end from beginning to end. Subgenomic mRNAs are created when transcription begins at the 3' end of the template strand (or 5' of the to-be-newly synthesized template) and begins to copy towards the 5' end of the template strand before "jumping" to the end of the template and copying the last nucleotides of ...

  6. Mumps virus - Wikipedia

    en.wikipedia.org/wiki/Mumps_virus

    Transcription starts at or near the 3'-end (usually pronounced "three prime end") at a promoter region and moves sequentially toward the 5'-end. One mRNA strand is transcribed for each gene, and it is necessary for all genes sequentially before a gene to be transcribed for that gene to be transcribed. Genes closer to the 3'-end are transcribed ...

  7. Polyadenylation - Wikipedia

    en.wikipedia.org/wiki/Polyadenylation

    By convention, RNA sequences are written in a 5′ to 3′ direction. The 5′ end is the part of the RNA molecule that is transcribed first, and the 3end is transcribed last. The 3end is also where the poly(A) tail is found on polyadenylated RNAs. [1] [9]

  8. Cis-acting replication element - Wikipedia

    en.wikipedia.org/wiki/Cis-acting_replication_element

    This is a rendering of cis-acting replication element inspired by an image of common cre structure found in Coronavirus from a review paper by Sola et al., 2015 [1]. Cis-acting replication elements (cre) bring together the 5′ and 3′ ends during replication of positive-sense single-stranded RNA viruses (for example Picornavirus, Flavivirus, Coronavirus, Togaviruses, Hepatitis C virus) and ...

  9. Sticky and blunt ends - Wikipedia

    en.wikipedia.org/wiki/Sticky_and_blunt_ends

    When a molecule of DNA is double stranded, as DNA usually is, the two strands run in opposite directions. Therefore, one end of the molecule will have the 3' end of strand 1 and the 5' end of strand 2, and vice versa in the other end. [2] However, the fact that the molecule is two stranded allows numerous different variations.