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A cobblestone throat occurs when inflamed bumps develop in the back of your throat. Infections, allergies, and acid reflux can all cause the bumps.
However, some researchers argue that the flow of mucus down the back of the throat from the nasal cavity is a normal physiologic process that occurs in all healthy individuals. [1] Some researchers challenge post-nasal drip as a syndrome and instead view it as a symptom, also taking into account variation across different societies.
It exhibits surface cells with vacuolated cytoplasm around irregular, pyknotic nuclei and occasional cells with mitosis-like changes within otherwise mature and well-differentiated epithelium. A distinguishing histologic feature is elongated rete ridges with mitosoid bodies. It shows 'cobblestone' appearance clinically.
Other symptoms include a metallic taste, throat closing or tightening, coughing fits, itchy throat, and choking. Larger tonsil stones may cause recurrent bad breath, which frequently accompanies a tonsil infection, sore throat , white debris, a bad taste in the back of the throat, difficulty swallowing, ear ache , and tonsil swelling. [ 12 ]
Esophageal candidiasis is an opportunistic infection of the esophagus by Candida albicans.The disease usually occurs in patients in immunocompromised states, including post-chemotherapy and in AIDS.
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During this exam, doctors closely examine the intestinal lining and take small tissue samples for further testing. Signs of Crohn's disease include uneven inflammation and 'skip lesions', which are patches of inflammation separated by healthy tissue. The ulcers can be small (less than 5 mm) or larger (over 5 mm), often appearing cobblestone-like.