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It is important to monitor a statistically representative population. Workers are often divided into "similar exposure groups" with similar work assignments and contaminant exposure profiles. Data must be validated, reported, and communicated. Exposure monitoring may be targeted to individual workers, or areas. [1]: 21, 46–47, 58
In analytical chemistry, the detection limit, lower limit of detection, also termed LOD for limit of detection or analytical sensitivity (not to be confused with statistical sensitivity), is the lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) with a stated confidence level (generally 99%).
Threshold limit value − time-weighted average (TLV-TWA): The average exposure on the basis of a 8 hours per day, 40 hours per week work schedule. Threshold limit value − short-term exposure limit (TLV-STEL): A 15-minute TWA exposure that should not be exceeded at any time during a workday, even if the 8-hour TWA is within the TLV-TWA.
A calibration curve plot showing limit of detection (LOD), limit of quantification (LOQ), dynamic range, and limit of linearity (LOL).. In analytical chemistry, a calibration curve, also known as a standard curve, is a general method for determining the concentration of a substance in an unknown sample by comparing the unknown to a set of standard samples of known concentration. [1]
National Institute for Occupational Safety and Health (NIOSH) RELs are designed to protect the health and well-being of workers by recommending safe exposure levels. To really use these guidelines well, safety professionals need to understand the recommended exposure levels, how to measure them, and ways to make sure workers aren't exposed to harmful stuff.
Among the major limitations are the underreporting of occupational health disorders, the inability to recognize potential occupational association of the disorder by health care workers, difficulties in attributing diseases with long latency or multiple causes (such as lung cancer) to occupational exposures, exclusion of special populations ...
The permissible exposure limit (PEL or OSHA PEL) is a legal limit in the United States for exposure of an employee to a chemical substance or physical agent such as high level noise. Permissible exposure limits were established by the Occupational Safety and Health Administration (OSHA). Most of OSHA's PELs were issued shortly after adoption of ...
There are different definitions within laboratory quality control, wherein "analytical sensitivity" is defined as the smallest amount of substance in a sample that can accurately be measured by an assay (synonymously to detection limit), and "analytical specificity" is defined as the ability of an assay to measure one particular organism or ...