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Bromoacetic acid is the chemical compound with the formula Br C H 2 CO 2 H. This colorless solid is a relatively strong alkylating agent . Bromoacetic acid and its esters are widely used building blocks in organic synthesis , for example, in pharmaceutical chemistry .
The tables below provides information on the variation of solubility of different substances (mostly inorganic compounds) in water with temperature, at one atmosphere pressure. Units of solubility are given in grams of substance per 100 millilitres of water (g/(100 mL)), unless shown otherwise. The substances are listed in alphabetical order.
The following chart shows the solubility of various ionic compounds in water at 1 atm pressure and room temperature (approx. 25 °C, 298.15 K). "Soluble" means the ionic compound doesn't precipitate, while "slightly soluble" and "insoluble" mean that a solid will precipitate; "slightly soluble" compounds like calcium sulfate may require heat to precipitate.
Methyl 2-bromoacetate is colorless or straw-colored liquid. The smell is sharp and penetrating. It is soluble in water and also has a higher density than water. [2] It is incompatible with acids, bases, oxidizing agents, and reducing agents. [3]
Ethyl bromoacetate is listed by the World Health Organization as a riot control agent, and was first employed for that purpose by French police in 1912. [4] The French army used rifle grenades 'grenades lacrymogènes' [5] filled with this gas against the Germans beginning in August 1914, but the weapons were largely ineffective, even though ethyl bromoacetate is twice as toxic as chlorine.
In a monohaloacetic acid, a single halogen replaces a hydrogen atom: for example, in bromoacetic acid. Further substitution of hydrogen atoms with halogens can occur, as in dichloroacetic acid and trichloroacetic acid. Haloacetic acids are a common contaminant in treated drinking water, particularly water subjected to chlorination.
In the search for more easily administered drugs, dapsone (1) was reacted with bromoacetic acid to give acediasulfone (2) which can be administered as a water-soluble salt. References [ edit ]
The solubility of a specific solute in a specific solvent is generally expressed as the concentration of a saturated solution of the two. [1] Any of the several ways of expressing concentration of solutions can be used, such as the mass, volume, or amount in moles of the solute for a specific mass, volume, or mole amount of the solvent or of the solution.