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Dilation and constriction of the pupil. Pupillary response is a physiological response that varies the size of the pupil, via the optic and oculomotor cranial nerve.. A constriction response (), [1] is the narrowing of the pupil, which may be caused by scleral buckles or drugs such as opiates/opioids or anti-hypertension medications.
Nerves involved in the resizing of the pupil connect to the pretectal nucleus of the high midbrain, bypassing the lateral geniculate nucleus and the primary visual cortex. From the pretectal nucleus neurons send axons to neurons of the Edinger-Westphal nucleus whose visceromotor axons run along both the left and right oculomotor nerves .
Opiate overdose symptoms and signs can be referred to as the "opioid toxidrome triad": decreased level of consciousness, pinpoint pupils and respiratory depression. Other symptoms include seizures and muscle spasms. Sometimes an opiate overdose can lead to such a decreased level of consciousness such that the person will not wake up.
Goose bumps can also be a response to anger or fear: the erect hairs make the animal appear larger, in order to intimidate enemies. This can be observed in the intimidation displays of chimpanzees, [ 11 ] some New World monkeys like the cotton-top tamarin , [ 12 ] in stressed mice [ 13 ] and rats, and in frightened cats.
It’s easier than ever for doctors to prescribe a key medicine for opioid addiction since the U.S. government lifted an obstacle last year. But despite the looser restrictions and the ongoing ...
The Big Book, first published in 1939, was the size of a hymnal. With its passionate appeals to faith made in the rat-a-tat cadence of a door-to-door salesman, it helped spawn other 12-step-based institutions, including Hazelden, founded in 1949 in Minnesota. Hazelden, in turn, would become a model for facilities across the country.
In fact, Patsy Ramsey has much bigger concerns. Almost from the moment the body of their 6-year-old daughter JonBenét was discovered, Boulder police believed John and Patsy killed their daughter ...
The motivation behind its exclusion from the CSA was that under the CSA, all optical isomers of listed Schedule II opiates are automatically Schedule II substances. Since dextromethorphan is an optical isomer of the Schedule II opiate levomethorphan (but does not act like an opiate), an exemption was necessary to keep it an uncontrolled substance.