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Clindamycin is a lincosamide antibiotic medication used for the treatment of a number of bacterial infections, including osteomyelitis (bone) or joint infections, pelvic inflammatory disease, strep throat, pneumonia, acute otitis media (middle ear infections), and endocarditis. [5]
Clindamycin/benzoyl peroxide, sold under the brand name Benzaclin among others, is a topical gel used for the treatment of acne. [7] It is a fixed-dose combination of clindamycin , as the phosphate, an antibiotic ; and benzoyl peroxide , an antiseptic .
Pseudomembranous enterocolitis resulting from clindamycin-induced disruption of gastrointestinal flora can be a lethal adverse event observed in several species when used in the veterinary clinic, particularly in horses. At extremely high doses of clindamycin, skeletal muscle paralysis has been demonstrated in several species.
It contains clindamycin, as the phosphate, a lincosamide antibacterial; adapalene, a synthetic retinoid; and benzoyl peroxide, an oxidizing agent. [2] It is applied to the skin . [ 2 ]
The Serbian Wikipedia (Serbian: Википедија на српском језику, Vikipedija na srpskom jeziku) is the Serbian-language version of the free online encyclopedia Wikipedia. Created on 16 February 2003, it reached its 100,000th article on 20 November 2009 before getting to another milestone with the 200,000th article on 6 July ...
A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom with inversion of chirality. [4] It was released for medical use in September 1964. [5]
Wikipedia is a free multilingual open-source wiki-based online encyclopedia edited and maintained by a community of volunteer editors, started on January 15th 2001 as an English-language encyclopedia.
Indeed, fosmidomycin has been tested in combination treatment with clindamycin for treatment of malaria with favorable results. [ 6 ] [ 7 ] [ 8 ] It has been shown that an increase in copy number of the target enzyme ( DXP reductoisomerase ) correlates with in vitro fosmidomycin resistance in the lethal malaria parasite, Plasmodium falciparum .