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A suspicious area on mammography or ultrasound. [9] This may include: Microcalcifications on MRI. [10] BI-RADS score of 4 or 5 on mammography, ultrasound, or MRI. [11] A suspicious hard palpable lump [9] Skin changes like crusting, scaling, or dimpling of the breast, which may signal an underlying breast cancer [9] Abnormal nipple discharge [7] [9]
The microscopic appearance of a nipple adenoma can be mistaken for carcinoma. [1] Other conditions that have similar symptoms and signs as nipple adenoma include Paget's disease of the breast, other intraductal papillomas, ductal carcinoma in situ (DCIS), syringomatous adenoma of the nipple and subareolar sclerosing duct hyperplasia.
A breast mass, also known as a breast lump, is a localized swelling that feels different from the surrounding tissue. [1] Breast pain , nipple discharge , or skin changes may be present. [ 1 ] Concerning findings include masses that are hard, do not move easily, are of an irregular shape, or are firmly attached to surrounding tissue.
Fibroadenoma of the breast is a benign tumor composed of a biplastic proliferation of both stromal and epithelial components. [ 12 ] [ 13 ] This biplasia can be arranged in two growth patterns: pericanalicular (stromal proliferation around epithelial structures) and intracanalicular (stromal proliferation compressing the epithelial structures ...
Automated whole-breast ultrasound (AWBU) is a technique that produces volumetric images of the breast and is largely independent of operator skill. It utilizes high-frequency ultrasound to help perform a diagnostic evaluation of the lactiferous ducts ( duct sonography ) [ 5 ] and make dilated ducts and intraductal masses visible.
Worldwide, breast cancer is the leading type of cancer in women, accounting for 25% of all cases. [5] It is most common in women over age 50. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. [6]
Adenomas are benign tumors of gland-forming cells, and are usually specified further by their cell or organ of origin, as in hepatic adenoma (a benign tumor of hepatocytes, or liver cells). Teratomas contain many cell types such as skin, nerve, brain and thyroid, among others, because they are derived from germ cells. [ 36 ]
Pseudoangiomatous stromal hyperplasia (PASH) is an overgrowth of myofibroblastic cells in the breast. It has an appearance similar to fibroadenomatoid changes. [1] The diagnostic significance is currently uncertain, but it appears to be benign. There have been cases of PASH diagnosed where the tumors co-exist with breast cancer.