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2. Haloperidol decanoate - Wikipedia

   en.wikipedia.org/wiki/Haloperidol_decanoate

   A 3.75-cm (1.5-inch), 21-gauge needle is generally used, but obese individuals may require a 6.5-cm (2.5-inch) needle to ensure that the drug is indeed injected intramuscularly and not subcutaneously. [6]

3. Dopamine antagonist - Wikipedia

   en.wikipedia.org/wiki/Dopamine_antagonist

   Haloperidol binds D 2, D 3 and D 4 with the highest affinity, but also binds D 1 and D 5. [1] [2] [3] Haloperidol also has a risk for QTc prolongation. [17] Fluphenazine binds D 2 and D 3 with the highest affinity but D 1 and D 5 as well [1] [2] Flupentixol binds D 1, D 2, D 3, and D 5 [2] and is also used as an antidepressant. [1] Fluspirilene ...

4. Haloperidol - Wikipedia

   en.wikipedia.org/wiki/Haloperidol

   Haloperidol is heavily protein bound in human plasma, with a free fraction of only 7.5 to 11.6%. It is also extensively metabolized in the liver with only about 1% of the administered dose excreted unchanged in the urine.

5. Extrapyramidal symptoms - Wikipedia

   en.wikipedia.org/wiki/Extrapyramidal_symptoms

   Although Parkinson's disease is primarily a disease of the nigrostriatal pathway and not the extrapyramidal system, loss of dopaminergic neurons in the substantia nigra leads to dysregulation of the extrapyramidal system. Since this system regulates posture and skeletal muscle tone, a result is the characteristic bradykinesia of Parkinson's.

6. NFL playoff watchability rankings: Which wild-card game is best?

   www.aol.com/nfl-playoff-watchability-rankings...

   3. No. 7 Green Bay Packers at No. 2 Philadelphia Eagles (Sunday, 4:30 p.m. ET, FOX) The health of Jalen Hurts (still in the concussion protocol) is the determining factor in this ranking.

7. Management of Parkinson's disease - Wikipedia

   en.wikipedia.org/wiki/Management_of_Parkinson's...

   In the management of Parkinson's disease, due to the chronic nature of Parkinson's disease (PD), a broad-based program is needed that includes patient and family education, support-group services, general wellness maintenance, exercise, and nutrition. At present, no cure for the disease is known, but medications or surgery can provide relief ...

8. Boeing still needs a culture change to put safety above ... - AOL

   www.aol.com/boeing-still-needs-culture-change...

   A year after a panel blew out of a Boeing 737 Max during flight, the nation’s top aviation regulator says the company needs "a fundamental cultural shift” to put safety and quality above profits.

9. The top 7 mental health challenges of the holidays and how to ...

   www.aol.com/top-7-mental-health-challenges...

   1. Family Relationships and Dynamics. Home is where the heart is, but family gatherings are at the heart of many holiday traditions. This is in part because they can also bring up unresolved ...