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  2. Gene structure - Wikipedia

    en.wikipedia.org/wiki/Gene_structure

    Gene structure is the organisation of specialised sequence elements within a gene.Genes contain most of the information necessary for living cells to survive and reproduce. [1] [2] In most organisms, genes are made of DNA, where the particular DNA sequence determines the function of the gene.

  3. Molecular Structure of Nucleic Acids: A Structure for ...

    en.wikipedia.org/wiki/Molecular_Structure_of...

    The two base-pair complementary chains of the DNA molecule allow replication of the genetic instructions. The "specific pairing" is a key feature of the Watson and Crick model of DNA, the pairing of nucleotide subunits. [5] In DNA, the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine. The A:T and C:G pairs ...

  4. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    DNA is read by DNA polymerase in the 3′ to 5′ direction, meaning the new strand is synthesized in the 5' to 3' direction. Since the leading and lagging strand templates are oriented in opposite directions at the replication fork, a major issue is how to achieve synthesis of new lagging strand DNA, whose direction of synthesis is opposite to ...

  5. List of genetic codes - Wikipedia

    en.wikipedia.org/wiki/List_of_genetic_codes

    The Balanophoraceae plastid code (not shown on web) [4] [5] The Cephalodiscidae mitochondrial code; The Enterosoma code [3] The Peptacetobacter code [3] The Anaerococcus and Onthovivens code [3] The Absconditabacterales code [3] The alternative translation tables (2 to 37) involve codon reassignments that are recapitulated in the DNA and RNA ...

  6. BED (file format) - Wikipedia

    en.wikipedia.org/wiki/BED_(file_format)

    3: chromEnd: End coordinate on the chromosome or scaffold for the sequence considered. This position is non-inclusive, unlike chromStart (the first base on the chromosome is numbered 1 i.e. the number is one-based). Yes 4: name: Name of the line in the BED file No 5: score: Score between 0 and 1000 No 6: strand

  7. Staden Package - Wikipedia

    en.wikipedia.org/wiki/Staden_Package

    The Staden Package was developed by Rodger Staden's group at the Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, England, since 1977. [2] [3] [4] The package was available free to academic users, with 2,500 licenses issued in 2003 and an estimated 10,000 users, when funding for further development ended. [5]

  8. Nucleic acid thermodynamics - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_thermodynamics

    For DNA oligonucleotides, i.e. short sequences of DNA, the thermodynamics of hybridization can be accurately described as a two-state process. In this approximation one neglects the possibility of intermediate partial binding states in the formation of a double strand state from two single stranded oligonucleotides.

  9. Genomic organization - Wikipedia

    en.wikipedia.org/wiki/Genomic_organization

    [1] [2] Only 1.2% of the mammalian genome thus encodes for protein function. This massive expansion of repetitive and noncoding sequences in multicellular organisms is most likely due to the incorporation of invasive elements, such as DNA transposons , retrotransposons , and other repetitive elements. [ 3 ]