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The two base-pair complementary chains of the DNA molecule allow replication of the genetic instructions. The "specific pairing" is a key feature of the Watson and Crick model of DNA, the pairing of nucleotide subunits. [5] In DNA, the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine. The A:T and C:G pairs ...
The Balanophoraceae plastid code (not shown on web) [4] [5] The Cephalodiscidae mitochondrial code; The Enterosoma code [3] The Peptacetobacter code [3] The Anaerococcus and Onthovivens code [3] The Absconditabacterales code [3] The alternative translation tables (2 to 37) involve codon reassignments that are recapitulated in the DNA and RNA ...
DNA is read by DNA polymerase in the 3′ to 5′ direction, meaning the new strand is synthesized in the 5' to 3' direction. Since the leading and lagging strand templates are oriented in opposite directions at the replication fork, a major issue is how to achieve synthesis of new lagging strand DNA, whose direction of synthesis is opposite to ...
The Staden Package was developed by Rodger Staden's group at the Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, England, since 1977. [2] [3] [4] The package was available free to academic users, with 2,500 licenses issued in 2003 and an estimated 10,000 users, when funding for further development ended. [5]
The Analysis page allows users to analyze the thermodynamic properties of a dilute solution of interacting nucleic acid strands in the absence of pseudoknots (e.g., a test tube of DNA or RNA strand species). [1] [3] For a dilute solution containing multiple strand species interacting to form multiple species of ordered complexes, NUPACK ...
Align DNA, RNA, protein, or DNA + protein sequences via a variety of pairwise and multiple sequence alignment algorithms, generate phylogenetic trees to predict evolutionary relationships, explore sequence tracks to view GC content, gap fraction, sequence logos, translation ABI, DNA Multi-Seq, FASTA, GCG Pileup, GenBank, Phred
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SAMtools is a set of utilities for interacting with and post-processing short DNA sequence read alignments in the SAM (Sequence Alignment/Map), BAM (Binary Alignment/Map) and CRAM formats, written by Heng Li.