Search results
Results from the WOW.Com Content Network
Congenital rubella syndrome (CRS) occurs when a human fetus is infected with the rubella virus (German measles) via maternal-fetal transmission and develops birth defects. [1] The most common congenital defects affect the ophthalmologic, cardiac, auditory, and neurologic systems.
Rubella is a common infection in many areas of the world. [2] Each year about 100,000 cases of congenital rubella syndrome occur. [3] Rates of disease have decreased in many areas as a result of vaccination. [2] [7] There are ongoing efforts to eliminate the disease globally. [3]
Rubella virus (RuV) is the pathogenic agent of the disease rubella, transmitted only between humans via the respiratory route, and is the main cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy.
Pregnant women with Rubella are at risk of having a miscarriage or having a baby born with multiple birth defects due to Congenital rubella syndrome. It affected around 12.5 million people in the US. An estimated 11,000 pregnancies ended in miscarriage or stillbirth , just over 2,000 newborn babies died , and of those that survived around ...
In 2000, the WHO established the Global Measles and Rubella Laboratory Network (GMRLN) to provide laboratory surveillance for measles, rubella, and congenital rubella syndrome. [106] Data from 2016 to 2018 show that the most frequently detected measles virus genotypes are decreasing, suggesting that increasing global population immunity has ...
The time of exposure to the virus also had a direct impact on the incidence of congenital malformations with exposure during week 4, 5–8 and 9–12 weeks of pregnancy caused 61%, 26% and 8% of congenital malformations. This was the first published recognition of congenital rubella syndrome (CRS).
In general, approximately one-third of congenital cataracts are a component of a more extensive syndrome or disease (e.g., cataract resulting from congenital rubella syndrome), one-third occur as an isolated inherited trait, and one-third result from undetermined causes.
Progressive rubella panencephalitis (PRP) is a neurological disorder which may occur in a child with congenital rubella. [1] It is a slow viral infection of the brain characterized by chronic encephalitis, usually manifesting between 8–19 years of age. It is believed to be due to a persistence or reactivation of rubella virus infection.