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Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety, obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [1]
It is also used as a treatment for depression and in pain management. [19] Ketamine is an NMDA receptor antagonist which accounts for most of its psychoactive effects. [20] At anesthetic doses, ketamine induces a state of dissociative anesthesia, a trance-like state providing pain relief, sedation, and amnesia. [21]
The results that have been published, about 70 studies, have been overwhelmingly positive in proving the safety and efficacy of ketamine as a mental health treatment. Ketamine was FDA-approved in ...
You may have also heard of ketamine therapy, which uses ketamine, a drug that was originally used as an animal anesthetic, administered in a clinical setting to improve mental health symptoms ...
Ketamine therapy in combination with exposure therapy has promising effects for the treatment of PTSD. [ 131 ] A systematic review of the literature found that ketamine therapy significantly reduced PTSD scores at the time of last follow-up while also significantly increasing the time to relapse versus control therapy.
A patient can choose between ketamine infusion therapy, where the patient takes a low dose of ketamine each session and sits at the clinic for about an hour; and ketamine-assisted therapy, during ...
Esketamine, sold under the brand name Spravato and produced by Janssen Pharmaceuticals, was approved by the FDA in March 2019 for the treatment of Treatment-Resistant Depression (TRD) and suicidal ideation. [8] As of 2022, it is the only psychoplastogen approved in the US for the treatment of a neuropsychiatric disorder. [6]
Ketamine also didn't result in lower rates of opioid prescribing in the months following treatment, a common goal of therapy, according to Gulur. Her research is under review for medical journal ...