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Albert Bruce Sabin (/ ˈ s eɪ b ɪ n / SAY-bin; born Abram Saperstejn; August 26, 1906 – March 3, 1993) was a Polish-American medical researcher, best known for developing the oral polio vaccine, which has played a key role in nearly eradicating the disease.
The risks and possible side effects of the polio vaccine are comparable to those of other vaccines, the CDC says, such as pain, soreness, swelling, and/or redness at the injection site. Fainting ...
Hypromellose , short for hydroxypropyl methylcellulose (HPMC), is a semisynthetic, inert, viscoelastic polymer used in eye drops, as well as an excipient and controlled-delivery component in oral medicaments, found in a variety of commercial products.
Many countries began polio immunization campaigns using Salk's vaccine, including Canada, Sweden, Denmark, Norway, West Germany, the Netherlands, Switzerland, and Belgium. By 1959, the Salk vaccine had reached about 90 countries. [5] An attenuated live oral polio vaccine was developed by Albert Sabin, coming into commercial use in 1961. Less ...
The epidemics ended with the introduction of the oral polio vaccine in 1962. – What is an iron lung? An iron lung is a respirator which stimulates breathing by enclosing a person’s body and ...
The second vaccine, an oral polio vaccine (OPV), is a live-attenuated vaccine, produced by the passage of the virus through non-human cells at a sub-physiological temperature. The passage of virus produces mutations within the viral genome, and hinders the virus's ability to infect nervous tissue. [6]
After the vaccines — there are two: trivalent inactivated poliovirus vaccine (IPV), introduced in 1955, and trivalent oral poliovirus vaccine (OPV) in 1963 — the number of polio cases ...
Numerous observational studies and randomised trials (RCTs) have found that the impact on mortality of live and inactivated vaccines differ markedly. All live vaccines studied so far (BCG, measles vaccine, oral polio vaccine (OPV) and smallpox vaccine) have been shown to reduce mortality more than can be explained by prevention of the targeted infection(s).