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In humans, hyperthermia is defined as a temperature greater than 37.5–38.3 °C (99.5–100.9 °F), depending on the reference used, that occurs without a change in the body's temperature set point. [3] [10] The normal human body temperature can be as high as 37.7 °C (99.9 °F) in the late afternoon. [2]
Drug-induced fever is a symptom of an adverse drug reaction wherein the administration of drugs intended to help a patient causes a hypermetabolic state resulting in fever. The drug may interfere with heat dissipation peripherally, increase the rate of metabolism , evoke a cellular or humoral immune response , mimic endogenous pyrogen , or ...
"Time to peak" refers to when maximum levels of the drug in the blood occur after a given dose. Benzodiazepines generally share the same pharmacological properties, such as anxiolytic, sedative, hypnotic, skeletal muscle relaxant, amnesic, and anticonvulsant effects. Variation in potency of certain effects may exist amongst individual ...
The human body is a collection of tissues with differing heat capacities, all connected by a dynamic circulatory system with variable relationship to skin or lung surfaces designed to shed heat energy. All methods of inducing higher temperature in the body are countered by the thermo-regulatory mechanisms of the body. The body as a whole relies ...
Heat illness is a spectrum of disorders due to increased body temperature. It can be caused by either environmental conditions or by exertion.It includes minor conditions such as heat cramps, heat syncope, and heat exhaustion as well as the more severe condition known as heat stroke. [1]
The human body always works to remain in homeostasis. One form of homeostasis is thermoregulation. Body temperature varies in every individual, but the average internal temperature is 37.0 °C (98.6 °F). [1] Sufficient stress from extreme external temperature may cause injury or death if it exceeds the ability of the body to thermoregulate.
The temperature reading depends on which part of the body is being measured. The typical daytime temperatures among healthy adults are as follows: Temperature in the anus (rectum/rectal), vagina, or in the ear (tympanic) is about 37.5 °C (99.5 °F) [20] [medical citation needed] Temperature in the mouth (oral) is about 36.8 °C (98.2 °F) [12]
Simplified control circuit of human thermoregulation. [8] The core temperature of a human is regulated and stabilized primarily by the hypothalamus, a region of the brain linking the endocrine system to the nervous system, [9] and more specifically by the anterior hypothalamic nucleus and the adjacent preoptic area regions of the hypothalamus ...