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Monoamines are connected to the pathophysiology of depression. Symptoms may occur because concentrations of neurotransmitters, such as norepinephrine and serotonin, are insufficient, leading to downstream changes. [10] [25] Medications for depression affect the transmission of serotonin, norepinephrine, and dopamine. [10]
[31] [32] Atomoxetine (Strattera) is another potent and selective NRI which is also effective and well tolerated treatment for adults with ADHD. This drug was the first ADHD treatment to be specially approved for adult use. Studies showed that atomoxetine is a nonstimulant and carries negligible risk of abuse.
Patients taking strong dopaminergic antagonists such as those used in the treatment of psychosis are more likely than the general population to develop symptoms of depression. [210] Data from clinical studies have shown that DA agonists, such as bromocriptine, pramipexole and ropinirole, exhibit antidepressant properties. [10]
Atomoxetine is sometimes used in the treatment of cognitive impairment and frontal lobe symptoms due to conditions like traumatic brain injury (TBI). [47] [48] It is used to treat ADHD-like symptoms such as sustained attentional problems, disinhibition, [49] lack of arousal, fatigue, and depression, including symptoms from cognitive disengagement syndrome. [47]
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
They note that about 30% of people with depression do not adequately respond to treatment. They say the subtypes may help identify potential treatment responses for things such as antidepressants ...
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