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  2. Deuruxolitinib - Wikipedia

    en.wikipedia.org/wiki/Deuruxolitinib

    Deuruxolitinib, sold under the brand name Leqselvi, is a medication used for the treatment of alopecia areata. [1] It is a Janus kinase inhibitor selective for JAK1 and JAK2 . [ 2 ] Although the relative effectiveness of deuruxolitinib and another Janus kinase inhibitor— baricitinib —for alopecia areata may vary depending on the population ...

  3. Janus kinase 3 inhibitor - Wikipedia

    en.wikipedia.org/wiki/Janus_kinase_3_inhibitor

    Currently, much attention is focused on developing Janus kinase inhibitors as drugs for immune diseases including inflammatory bowel diseases, rheumatoid arthritis, alopecia areata, and psoriases. [12] The first JAK inhibitor approved for the treatment of rheumatoid arthritis was tofacitinib. It has also shown promising results in other ...

  4. Janus kinase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Janus_kinase_inhibitor

    A Janus kinase inhibitor, also known as JAK inhibitor or jakinib, [1] is a type of immune modulating medication, which inhibits the activity of one or more of the Janus kinase family of enzymes (JAK1, JAK2, JAK3, TYK2), thereby interfering with the JAK-STAT signaling pathway in lymphocytes.

  5. Baricitinib - Wikipedia

    en.wikipedia.org/wiki/Baricitinib

    Baricitinib is a Janus kinase (JAK) inhibitor that reversibly inhibits Janus kinase 1 with a half maximal inhibitory concentration (IC 50) of 5.9 nM and Janus kinase 2 with an IC 50 of 5.7 nM. Tyrosine kinase 2 , which belongs to the same enzyme family, is affected less (IC 50 = 53 nM), and Janus kinase 3 far less (IC 50 > 400 nM).

  6. Hair Loss in Women: Everything You Need to Know - AOL

    www.aol.com/hair-loss-women-everything-know...

    Alopecia areata, on the other hand, is caused by an autoimmune disease. It happens when your immune system mistakenly attacks hair follicles. Stress is the main driver of telogen effluvium.

  7. Ivarmacitinib - Wikipedia

    en.wikipedia.org/wiki/Ivarmacitinib

    Ivarmacitinib (SHR0302) is a small molecule drug and selective janus kinase 1 (JAK1) inhibitor. It is being developed for ulcerative colitis , [ 1 ] eczema , alopecia areata , and graft-versus-host disease .

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