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Common side effects for oral decongestants include insomnia, hypertension (elevated blood pressure), and difficulty in urination. [12] Avoid use during pregnancy as it may cause vasoconstriction of uterine arteries thus reducing fetal blood supply. [14] Zyrtec-D, an example of combination therapy. Combination therapy with antihistamines
Its levels increase during pregnancy to prepare the breasts for milk production and remain high after childbirth to continue supporting breastfeeding. Issues related to abnormal lactation, such as inadequate milk supply or galactorrhea, an excessive milk flow not linked to childbirth, are also explored.
[4] [5] Use is not recommended during pregnancy. [2] Xylometazoline is in the decongestant and alpha-adrenergic agonist families of medication. [5] [6] One study classified it with selectivity ratios in alpha 2 adrenergic receptors of 151 for a2A vs a2B, 4.5 a2A vs a2C, and 33.9 a2B vs a2C. Making it a highly selective a2A agonist. [7]
Decongestants are often used in conjunction with cold medications or to combat pregnancy rhinitis in pregnant women. Common decongestants include pseudoephedrine and phenylephrine . [ 14 ] Pseudoephedrine is an alpha-adrenergic receptor agonist that enacts a vasoconstrictive effect to reduce airflow resistance in the nasal cavity and allow ...
Use during pregnancy appears to be safe but has not been well studied. [7] It is not recommended in children less than two years old. [6] It is in the second-generation antihistamine family of medication. [5] Loratadine was patented in 1980 and came to market in 1988. [8] It is on the World Health Organization's List of Essential Medicines. [9]
For children suffering from allergies, Reigart says saline nose drops or first generation antihistamines such as Benadryl can be beneficial for congestion. But oftentimes, you can skip the meds.
Propylhexedrine, sold under the brand name Benzedrex among others, is an alkylamine primarily utilized as a topical nasal decongestant. [1] Its main indications are relief of congestion due to colds, allergies, and allergic rhinitis. [2]
Use in pregnancy appears safe, but use during breastfeeding is not recommended. [9] The medication works by blocking histamine H 1 receptors, mostly outside the brain. [6] Cetirizine can be used for paediatric patients. The main side effect to be cautious about is somnolence. [10] It was patented in 1983 [11] [12] and came into medical use in ...