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  2. Organophosphate poisoning - Wikipedia

    en.wikipedia.org/wiki/Organophosphate_poisoning

    Organophosphate poisoning is poisoning due to organophosphates (OPs). [4] Organophosphates are used as insecticides , medications, and nerve agents . [ 4 ] Symptoms include increased saliva and tear production, diarrhea , vomiting, small pupils , sweating, muscle tremors, and confusion. [ 2 ]

  3. Toxic oil syndrome - Wikipedia

    en.wikipedia.org/wiki/Toxic_oil_syndrome

    Toxic oil syndrome (TOS) or simply toxic syndrome (Spanish: síndrome del aceite tóxico or síndrome tóxico) is a musculoskeletal disease.A 1981 outbreak in Spain which affected about 25,600 people, with over 4,000 dying within a few months and a few thousand remaining disabled, is thought to have been caused by contaminated colza (rapeseed) oil.

  4. Gaps in regulation of chemical agents - Wikipedia

    en.wikipedia.org/wiki/Gaps_in_regulation_of...

    Test levels from the following week increase by 5% and the week after that by 14%. Over the course of time, their levels kept increasing. This is believed to be due to organophosphates inhibiting the enzyme, cholinesterase, resulting in toxic effects by allowing an increase of the neurotransmitter in the nervous system.

  5. Pesticide poisoning - Wikipedia

    en.wikipedia.org/wiki/Pesticide_poisoning

    A few additional screening questions about the patient's work and home environment, in addition to a typical health questionnaire, can indicate whether there was a potential pesticide poisoning. [24] If one is regularly using carbamate and organophosphate pesticides, it is important to obtain a baseline cholinesterase test.

  6. Organophosphate-induced delayed neuropathy - Wikipedia

    en.wikipedia.org/wiki/Organophosphate-induced...

    Organophosphate-induced delayed neuropathy (OPIDN), also called organophosphate-induced delayed polyneuropathy (OPIDP), is a neuropathy caused by killing of neurons in the central nervous system, especially in the spinal cord, as a result of acute or chronic organophosphate poisoning.

  7. Sarin - Wikipedia

    en.wikipedia.org/wiki/Sarin

    The toxicity of sarin in humans is largely based on calculations from studies with animals. The lethal concentration of sarin in air is approximately 28–35 mg per cubic meter per minute for a two-minute exposure time by a healthy adult breathing normally (exchanging 15 liters of air per minute, lower 28 mg/m 3 value is for general population ...

  8. Organophosphate - Wikipedia

    en.wikipedia.org/wiki/Organophosphate

    Organophosphate insecticides are acetylcholinesterase inhibitors, which disrupt the transmission of nerve signals in exposed organisms, with fatal results. The risk of human death through organophosphate poisoning [33] was obvious from the start and led to efforts to lower toxicity against mammals while not reducing efficacy against insects ...

  9. Pralidoxime - Wikipedia

    en.wikipedia.org/wiki/Pralidoxime

    Pralidoxime (2-pyridine aldoxime methyl chloride) or 2-PAM, usually as the chloride or iodide salts, belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. [1] It is used to treat organophosphate poisoning [2] in conjunction with atropine and either diazepam or midazolam. It is a white solid.