Search results
Results from the WOW.Com Content Network
Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. [ 1 ] [ 2 ] If there is decreased secretion of one specific pituitary hormone, the condition is known as selective hypopituitarism. [ 3 ]
Sheehan's syndrome, also known as postpartum pituitary gland necrosis, occurs when the pituitary gland is damaged due to significant blood loss and hypovolemic shock (ischemic necrosis) or stroke, originally described during or after childbirth leading to decreased functioning of the pituitary gland (hypopituitarism). [1]
Hypogonadotropic hypogonadism (HH), is due to problems with either the hypothalamus or pituitary gland affecting the hypothalamic-pituitary-gonadal axis (HPG axis). [1] ...
Hypopituitarism, the decreased (hypo) secretion of one or more of the hormones normally produced by the pituitary gland; Panhypopituitarism a decreased secretion of most of the pituitary hormones; Pituitary tumours; Pituitary adenomas, noncancerous tumors that occur in the pituitary gland
Examples of pituitary defects include hypopituitarism and pituitary hypoplasia. An example of a hypogonadism resulting from the lack of hormone response is androgen insensitivity syndrome, where there are inadequate receptors to bind the testosterone, resulting in varying clinical phenotypes of sexual characteristics despite XY chromosomes. [3]
However, clinical, laboratory data, and imaging can all help with the diagnosis.[8] First and foremost, patients present with symptoms of hypopituitarism and must undergo pituitary hormone function evaluation. [1] Biopsy is the only means of accurate diagnosis as no autoantigen has been discovered.
congenital hypopituitarism, holoprosencephaly [3] Septo-optic dysplasia ( SOD ), known also as de Morsier syndrome , is a rare congenital malformation syndrome that features a combination of the underdevelopment of the optic nerve , pituitary gland dysfunction, and absence of the septum pellucidum (a midline part of the brain).
PSIS is a common cause of congenital hypopituitarism, and causes a permanent growth hormone deficit. Some PSIS-affected individuals may also present with adrenal hypoplasia (5–29%), diabetes insipidus (5–29%), primary amenorrhea (5–29%), hypothyroidism (30–79%), failure to thrive (80–99%), septooptic dysplasia (5–29%), and Fanconi ...