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Security clearances can be issued by many United States of America government agencies, including the Department of Defense (DoD), the Department of State (DOS), the Department of Homeland Security (DHS), the Department of Energy (DoE), the Department of Justice (DoJ), the National Security Agency (NSA), and the Central Intelligence Agency (CIA).
The gene is located on the long arm of chromosome 14 (14q32.1).. Over 100 different variants of α 1-antitrypsin have been described in various populations.North-Western Europeans are most at risk for carrying one of the most common mutant forms of A1AT, the Z mutation (Glu342Lys on M1A, rs28929474).