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Collagen (/ ˈ k ɒ l ə dʒ ə n /) is the main structural protein in the extracellular matrix of a body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals. [1] 25% to 35% of a mammalian body's protein content is collagen.
Connective tissue is found in between other tissues everywhere in the body, including the nervous system. The three meninges, membranes that envelop the brain and spinal cord, are composed of connective tissue. Most types of connective tissue consists of three main components: elastic and collagen fibers, ground substance, and cells. [2]
Collagen is a protein that strengthens and supports many tissues in the body, including cartilage, bone, tendon, skin and the white part of the eye . The COL1A1 gene produces a component of type I collagen , called the pro-alpha1(I) chain.
Type I collagen can be found in a myriad of different places in the body, mainly forming the matrix of connective tissues. It is present in scar tissue as well as tendons , ligaments , the endomysium of myofibrils , the organic part of bone , the dermis , the dentin , and organ capsules.
Collagen, a key component of the animal extracellular matrix, is made through cleavage of pro-collagen by collagenase once it has been secreted from the cell. This stops large structures from forming inside the cell itself. In addition to being produced by some bacteria, collagenase can be made by the body as part of its normal immune response.
Though one's body produces peptides naturally, peptides are also found in many food and supplement sources. "All the food we eat is broken down by the body into amino acids," explains Stevenson.
A fibroblast is a type of biological cell typically with a spindle shape [1] that synthesizes the extracellular matrix and collagen, [2] produces the structural framework for animal tissues, and plays a critical role in wound healing. [3] Fibroblasts are the most common cells of connective tissue in animals.
Vitamin C comes with a whole host of benefits, including immune-system support and anti-aging help. Finally, there’s vitamin E, an ingredient loaded with antioxidants that seek out free-radical ...
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